Clopyralid

Clopyralid

SCHEMBL6933656

CCOC(=O)C(C)N(C(=O)c1ccccc1)c1ccc(Cl)c(Cl)c1.O=C(O)c1nc(Cl)ccc1Cl

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.41
CYP1A2 P05177 1/20 0.39
RORC P51449 1/20 0.38
ALDH1A1 P00352 1/20 0.38
CTSA P10619 1/20 0.37
GAA P10253 1/20 0.37
CHRM2 P08172 1/20 0.37
CHRM3 P20309 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
PLA2G1B P04054 1/20 0.36
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ATG4B Q9Y4P1 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
ADORA1 P30542 1/20 0.36
LMNA P02545 1/20 0.35
PTGDR2 Q9Y5Y4 1/20 0.35
NPC1 O15118 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6294014 0.89 RORC (0.45) CYP1A2RORCALDH1A1CHRM2CHRM3
SCHEMBL163055 0.89 RORC (0.45) CYP1A2RORCALDH1A1CHRM2CHRM3
SCHEMBL8827400 0.89 RORC (0.45) CYP1A2RORCALDH1A1CHRM2CHRM3
SCHEMBL8540022 0.86 RORC (0.43) RORCALDH1A1CHRM2CHRM3MEN1
SCHEMBL11284170 0.80 MEN1 (0.46) RORCALDH1A1CHRM2CHRM3MEN1
SCHEMBL635895 0.79 RORC (0.43) L3MBTL1RORCALDH1A1MEN1KMT2A
SCHEMBL635894 0.79 RORC (0.43) L3MBTL1RORCALDH1A1MEN1KMT2A
SCHEMBL9617379 0.78 KMT2A (0.54) CYP1A2ALDH1A1CHRM2CHRM3MEN1
SCHEMBL10858376 0.76 MEN1 (0.42) RORCALDH1A1CHRM2CHRM3MEN1
SCHEMBL11478132 0.75 NPC1 (0.48) CYP1A2ALDH1A1GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6653258-B1 Pyridinyl-substituted- methyl 3-methoxy-2-phenylacrylate derivatives; agricultural miticides and nematocides SYNGENTA LIMITED (GB) 2003-11-25 US disclosed
US-6566547-B1 3-alkoxy-2-phenylacrylic acid derivatives ZENECA LIMITED (GB) 2003-05-20 US disclosed
EP-0178826-B2 Fungicides SYNGENTA LTD (GB) 2003-04-09 EP disclosed
EP-0274825-B1 Indole derivatives and their uses in agriculture SYNGENTA LTD (GB) 2002-09-11 EP disclosed
EP-0278595-B2 Fungicides ZENECA LTD (GB) 2000-01-12 EP disclosed
US-5602076-A INSECTICIDES, NEMATOCIDES ZENECA LIMITED (GB) 1997-02-11 US disclosed
EP-0312243-B1 Methyl 2-[2-(3-substituted phenoxy)pyridin-3-yl]-3-methoxypropenoatesand their use as fungicides ZENECA LTD (GB) 1996-08-07 EP disclosed
EP-0273572-B1 Pyrrole derivatives and their use in agriculture ZENECA LTD (GB) 1996-01-24 EP disclosed
US-5470819-A Plant growth regulators, insecticides ZENECA LIMITED (GB) 1995-11-28 US disclosed
US-5468857-A Phenylmethoxypropenoic esters IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1995-11-21 US disclosed
EP-0120609-A2 Fungicidal azolyl-ethyl-phosphonate derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-10-03 EP disclosed
EP-0114487-A2 Fungicidal azolylethanol derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-08-01 EP disclosed
EP-0099165-A1 Triazole and imidazole compounds, process for their preparation and their use as fungicides and plant growth regulators, and intermediates for their synthesis IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-01-25 EP disclosed
EP-0097426-A2 Triazole compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-01-04 EP disclosed
EP-0089100-A2 Azolyl derivatives as fungicides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-09-21 EP disclosed
EP-0086917-A1 Heterocyclic compounds useful as pesticides and processes for making them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-08-31 EP disclosed
EP-0086304-A1 Heterocyclic compounds useful as pesticides and processes for making them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-08-24 EP disclosed
EP-0076030-A2 Substituted amide derivatives, processes for preparing them, pesticidal compositions containing them and processes for combating unwanted vegetation and fungi IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-04-06 EP disclosed
EP-0061840-A2 Triazole compounds, a process for preparing them, their use as plant fungicides and fungicidal compositions containing them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-10-06 EP disclosed
EP-0052424-A2 Triazole compounds, a process for preparing them, their use as plant fungicides and fungicidal compositions containing them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-05-26 EP disclosed