SCHEMBL6294014

SCHEMBL6294014

CCOC(=O)[C@H](C)N(C(=O)c1ccccc1)c1ccc(Cl)c(Cl)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORC P51449 1/20 0.45
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
HTT P42858 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
PLA2G1B P04054 1/20 0.43
ATG4B Q9Y4P1 1/20 0.43
CHRM2 P08172 1/20 0.43
CHRM3 P20309 1/20 0.43
NPC1 O15118 1/20 0.43
ALDH1A1 P00352 3/20 0.42
LMNA P02545 2/20 0.41
KDM4E B2RXH2 1/20 0.40
MAPT P10636 3/20 0.40
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
POLB P06746 1/20 0.39
PPARG P37231 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8827400 1.00 RORC (0.45) RORCMEN1KMT2AHTTNPSR1
SCHEMBL163055 1.00 RORC (0.45) RORCMEN1KMT2AHTTNPSR1
SCHEMBL8540022 0.96 RORC (0.43) RORCMEN1KMT2AHTTNPSR1
SCHEMBL11284170 0.89 MEN1 (0.46) RORCMEN1KMT2AHTTNPSR1
Clopyralid SCHEMBL6933656 0.89 L3MBTL1 (0.41) RORCMEN1KMT2AHTTNPSR1
SCHEMBL635894 0.89 RORC (0.43) RORCMEN1KMT2AHTTNPSR1
SCHEMBL635895 0.89 RORC (0.43) RORCMEN1KMT2AHTTNPSR1
SCHEMBL9617379 0.87 KMT2A (0.54) MEN1KMT2AHTTNPSR1PLA2G1B
SCHEMBL10858376 0.85 MEN1 (0.42) RORCMEN1KMT2AHTTNPSR1
SCHEMBL4894608 0.84 CHRM2 (0.45) MEN1KMT2AHTTNPSR1CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2836072-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT Dongbu Farm Hannong Co., Ltd. (KR) 2015-02-18 EP claimed
US-20150024940-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT DONGBU FARM HANNONG CO., LTD. (KR) 2015-01-22 US claimed
WO-2013154396-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT DONGBU FARM HANNONG CO., LTD. (KR) 2013-10-17 WO claimed
US-20050192182-A1 Herbicidal mixtures based on substituted aryl ketones BAYER CROPSCIENCE AG (DE) 2005-09-01 US claimed
US-20050090397-A1 Herbicides made from substituted aryl ketones BAYER CROPSCIENCE AG (GB) 2005-04-28 US claimed
US-6849578-B1 Selective herbicides based on 2,6-disubstituted pyridine derivatives BAYER AKTIENGESELLSCHAFT (DE) 2005-02-01 US claimed
US-20040171488-A1 N-aryl-uracils based Herbicides FEUCHT DIETER (DE) 2004-09-02 US claimed
EP-1423009-A2 HERBICIDES MADE FROM SUBSTITUTED ARYL KETONES Bayer CropScience AG (DE) 2004-06-02 EP claimed
EP-1372395-A1 HERBICIDES BASED ON SUBSTITUTED ARYL KETONES Bayer CropScience AG (DE) 2004-01-02 EP claimed
EP-1351571-A2 SELECTIVE HERBICIDES BASED UPON 2,6-DISUBSTITUTED PYRIDINE DERIVATIVES Bayer CropScience AG (DE) 2003-10-15 EP claimed
EP-1221848-A1 SELECTIVE HERBICIDES ON THE BASIS OF N-ARYL-TRIAZOLINE(THI)ONES Bayer Aktiengesellschaft (DE) 2002-07-17 EP claimed
US-20010056040-A1 Controlling weeds; synergistic mixtures BAYER AKTIENGESELLSCHAFT KONZERNBEREICH RP PATENT UND LIZENZEN (DE) 2001-12-27 US claimed
WO-2001039597-A2 N-ARYL-URACILE-BASED HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-06-07 WO claimed
WO-2001037652-A2 CARBAMOYL TRIAZOLINONE-BASED HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-05-31 WO claimed
WO-2001035741-A2 SYNERGISTIC HERBICIDAL ACTIVE SUBSTANCE COMBINATIONS BAYER AKTIENGESELLSCHAFT (DE) 2001-05-25 WO claimed
WO-2001035740-A2 SELECTIVE HERBICIDES BASED UPON 2,6-DISUBSTITUTED PYRIDINE DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2001-05-25 WO claimed
WO-2001022819-A1 SELECTIVE HERBICIDES ON THE BASIS OF N-ARYL-TRIAZOLINE(THI)ONES BAYER AKTIENGESELLSCHAFT (DE) 2001-04-05 WO claimed
EP-0929221-A1 SELECTIVE HERBICIDES BASED ON ARYLSULPHONYLAMINOCARBONYLTRIAZOLINONES BAYER AG (DE) 1999-07-21 EP claimed
WO-1998012923-A1 SELECTIVE HERBICIDES BASED ON ARYLSULPHONYLAMINOCARBONYLTRIAZOLINONES BAYER AKTIENGESELLSCHAFT (DE) 1998-04-02 WO claimed
US-5217524-A 1,5-diphenyl-1,2,4-triazole-3-carboxylic acid derivatives for the protection of cultivated plants from the phytotoxic action of herbicides CIBA-GEIGY CORPORATION (US) 1993-06-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050192182-A1 Herbicidal mixtures based on substituted aryl ketones DDT, CBR3, CYP1B1 RORC 1554/4885MEN1 4659/4885KMT2A 505/4885
US-20150024940-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT UNG, DDT, HDHD5 RORC 3745/4885MEN1 4570/4885KMT2A 766/4885
US-20050090397-A1 Herbicides made from substituted aryl ketones DDT, CBR3, CBR1 RORC 1676/4885MEN1 4607/4885KMT2A 405/4885
US-20040171488-A1 N-aryl-uracils based Herbicides DDT, UNG, DDC RORC 2903/4885MEN1 4777/4885KMT2A 647/4885
US-20010056040-A1 Controlling weeds; synergistic mixtures AS3MT, OSR1, MSRB3 RORC 2271/4885MEN1 2086/4885KMT2A 1606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.