Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.58 |
| ▸ | PTPRC | P08575 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | S100A4 | P26447 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16731600 | 0.92 | S100A4 (0.59) | TTRPTPRCMAPTNPC1LMNA | |
| SCHEMBL6934221 | 0.91 | TTR (0.65) | TTRPTPRCMAPTNPC1LMNA | |
| SCHEMBL6933741 | 0.89 | TTR (0.67) | TTRPTPRCMAPTNPC1LMNA | |
| SCHEMBL8717537 | 0.80 | LMNA (0.67) | MAPTLMNASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL13849150 | 0.79 | TTR (0.63) | TTRPTPRCMAPTNPC1LMNA | |
| SCHEMBL11579212 | 0.79 | TTR (0.63) | TTRPTPRCMAPTNPC1LMNA | |
| SCHEMBL545343 | 0.78 | LMNA (0.58) | MAPTLMNARAB9ASMN1; SMN2ALDH1A1 | |
| Hydrogen Peroxide SCHEMBL27952375 | 0.78 | LMNA (0.70) | MAPTLMNASMN1; SMN2ALDH1A1L3MBTL1 | |
| Benzene SCHEMBL27793442 | 0.78 | LMNA (0.70) | MAPTLMNASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL52413 | 0.78 | LMNA (0.70) | MAPTLMNASMN1; SMN2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210388161-A1 | METHOD OF MAKING RELEASABLE POLYMERIC REAGENTS | NEKTAR THERAPEUTICS | 2021-12-16 | — | — | US | disclosed |
| US-20200276320-A1 | COMPOSITION COMPRISING A POLYMERIC REAGENT | NEKTAR THERAPEUTICS (US) | 2020-09-03 | — | — | US | disclosed |
| US-20150141665-A1 | METHODS FOR PREPARING POLYMERIC REAGENTS | NEKTAR THERAPEUTICS (US) | 2015-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200276320-A1 | COMPOSITION COMPRISING A POLYMERIC REAGENT | CD44, FCGRT, C9 | TTR 774/4885PTPRC 553/4885MAPT 1479/4885 |
| US-20150141665-A1 | METHODS FOR PREPARING POLYMERIC REAGENTS | PAM, ALKBH3, DNPEP | TTR 1127/4885PTPRC 1029/4885MAPT 3976/4885 |
| US-20210388161-A1 | METHOD OF MAKING RELEASABLE POLYMERIC REAGENTS | FGB, PCBP1, PFAS | TTR 875/4885PTPRC 364/4885MAPT 2710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.