Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 7/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6805074 | 0.84 | ACACB (0.37) | KDM4EHPGDHSD17B10ACACBLMNA | |
| SCHEMBL6556019 | 0.72 | PARP1 (0.50) | KDM4EHPGDHSD17B10LMNAMTNR1A | |
| SCHEMBL18196600 | 0.70 | HPGD (0.42) | KDM4EHPGDHSD17B10LMNAMTNR1A | |
| Oxalic Acid SCHEMBL11719164 | 0.67 | POLB (0.48) | KDM4ELMNAMAPT | |
| SCHEMBL5200399 | 0.66 | MTNR1A (0.47) | KDM4EHPGDHSD17B10MTNR1AMAPT | |
| SCHEMBL11708040 | 0.65 | CYP1A2 (0.62) | CYP1A2 | |
| SCHEMBL28471767 | 0.65 | ACKR3 (0.39) | PRMT5WDR77 | |
| SCHEMBL28469182 | 0.64 | ACKR3 (0.45) | PRMT5WDR77 | |
| SCHEMBL11709331 | 0.64 | KCNH2 (0.50) | CYP1A2MAPT | |
| SCHEMBL11708757 | 0.62 | SIGMAR1 (0.50) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370296-A2 | CATECHOLATE BETA-LACTAM CONJUGATES, METHOD FOR PRODUCING THE SAME AND THE USE THEREOF | Grünenthal GmbH (DE) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002070016-A2 | CATECHOLATE BETA-LACTAM CONJUGATES, METHOD FOR PRODUCING THE SAME AND THE USE THEREOF | Grünenthal GmbH (DE) | 2002-09-12 | — | — | WO | disclosed |