Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | BRD2 | P25440 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942517 | 0.90 | NR3C1 (0.45) | NR3C1PTGS2BRD4BRD2CREBBP | |
| SCHEMBL6937716 | 0.86 | BACE1 (0.45) | TP53CYP3A4BACE1MAPK1RAB9A | |
| SCHEMBL29450716 | 0.86 | BACE1 (0.45) | TP53CYP3A4BACE1MAPK1RAB9A | |
| SCHEMBL6938211 | 0.83 | PTGS2 (0.45) | NR3C1PTGS2BRD4BRD2CREBBP | |
| SCHEMBL8665749 | 0.76 | BACE1 (0.39) | MAPTTHRBBACE1RAB9A | |
| SCHEMBL6938978 | 0.75 | BACE1 (0.45) | CYP3A4BACE1MAPK1HSD17B10 | |
| SCHEMBL29450715 | 0.75 | BACE1 (0.45) | CYP3A4BACE1MAPK1HSD17B10 | |
| SCHEMBL6941966 | 0.72 | DYRK1A (0.43) | NOTUMDHODHCYP3A4BACE1 | |
| SCHEMBL6941655 | 0.72 | DYRK1A (0.43) | NOTUMKDM4EMAPTTDP1TP53 | |
| SCHEMBL29417503 | 0.72 | DYRK1A (0.43) | NOTUMKDM4EMAPTTDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6524770-B1 | For polyimide precursor curable under patternwise low radiation; heat and chemical resistance; polyamide having unsaturated ester pendant groups cures | HITACHI CHEMICAL CO., LTD. (JP) | 2003-02-25 | — | — | US | disclosed |