Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.54 |
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4904149 | 0.75 | SMN1; SMN2 (0.55) | SMN1; SMN2RAB9ANPC1HPGDL3MBTL1 | |
| SCHEMBL6939920 | 0.73 | BCAT2 (0.46) | SMN1; SMN2RAB9AHPGDL3MBTL1MAPT | |
| SCHEMBL7029342 | 0.72 | SMN1; SMN2 (0.52) | SMN1; SMN2RAB9ANPC1HPGDL3MBTL1 | |
| SCHEMBL6939168 | 0.72 | HPGD (0.37) | SMN1; SMN2RAB9ANPC1HPGDL3MBTL1 | |
| SCHEMBL1752792 | 0.71 | SMN1; SMN2 (0.71) | SMN1; SMN2RAB9ANPC1HPGDL3MBTL1 | |
| SCHEMBL6940074 | 0.71 | LMNA (0.40) | SMN1; SMN2RAB9ANPC1HPGDL3MBTL1 | |
| SCHEMBL15304943 | 0.71 | SMN1; SMN2 (0.50) | SMN1; SMN2RAB9ANPC1HPGDL3MBTL1 | |
| SCHEMBL1752819 | 0.71 | RAB9A (0.62) | SMN1; SMN2RAB9ANPC1HPGDL3MBTL1 | |
| SCHEMBL2493590 | 0.71 | RAB9A (0.62) | SMN1; SMN2RAB9ANPC1HPGDL3MBTL1 | |
| SCHEMBL15633214 | 0.70 | L3MBTL1 (0.56) | SMN1; SMN2RAB9ANPC1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1147477-C | Novel allylthiopyridazine derivative and process for producing the same | ��ʽ���纺����ҩ | 2004-04-28 | — | — | CN | disclosed |
| EP-1058681-B1 | NOVEL ALLYLTHIOPYRIDAZINE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | SEOUL PHARM CO LTD (KR) | 2003-05-07 | — | — | EP | disclosed |
| EP-1058681-A1 | NOVEL ALLYLTHIOPYRIDAZINE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | Seoul Pharm. Co., Ltd. (KR) | 2000-12-13 | — | — | EP | disclosed |
| US-5942511-A | PROTECTION OF HUMAN TISSUE FROM RADIATION | Kwon, Soon Kyoung (KR) | 1999-08-24 | — | — | US | disclosed |
| WO-1999036407-A1 | NOVEL ALLYLTHIOPYRIDAZINE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | SEOUL PHARM. CO., LTD. (KR) | 1999-07-22 | — | — | WO | disclosed |
| US-4623376-A | PRE- AND POSTEMERGENCE | AMERICAN CYANAMID COMPANY (US) | 1986-11-18 | — | — | US | disclosed |