Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3854785 | 0.98 | KMT2A (0.56) | KMT2AALDH1A1MEN1RCE1GAA | |
| SCHEMBL14008412 | 0.77 | ALDH1A1 (0.55) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2953104 | 0.76 | ALDH1A1 (0.50) | KMT2AALDH1A1MEN1 | |
| Bromide SCHEMBL8389740 | 0.75 | ALDH1A1 (0.38) | KMT2AALDH1A1MEN1RCE1GAA | |
| SCHEMBL6935658 | 0.73 | ALDH1A1 (0.47) | KMT2AALDH1A1MEN1GAA | |
| Bromide SCHEMBL2955255 | 0.72 | ALDH1A1 (0.50) | KMT2AALDH1A1MEN1GAA | |
| SCHEMBL12118318 | 0.71 | KMT2A (0.96) | KMT2AALDH1A1MEN1RCE1GAA | |
| SCHEMBL7074123 | 0.63 | ALDH1A1 (0.69) | KMT2AALDH1A1MEN1GAA | |
| SCHEMBL31623847 | 0.63 | — | — | |
| SCHEMBL9854811 | 0.58 | KMT2A (0.37) | KMT2AALDH1A1MEN1RCE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808163-B1 | USE OF THIAZOLIUM COMPOUNDS FOR PREVENTING AND REVERSING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS | ALTEON INC (US) | 2003-07-23 | — | — | EP | claimed |
| US-6440749-B1 | ADMINISTERING A THIAZOLE COMPOUND | ALTEON. INC. | 2002-08-27 | — | — | US | claimed |