Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3849524 | 0.98 | ALDH1A1 (0.72) | ALDH1A1PABPC1USP2GSK3BMEN1 | |
| SCHEMBL14008410 | 0.84 | ALDH1A1 (0.69) | ALDH1A1PABPC1MEN1KMT2AKDM4E | |
| SCHEMBL7074123 | 0.84 | ALDH1A1 (0.69) | ALDH1A1PABPC1MEN1KMT2AKDM4E | |
| SCHEMBL6935140 | 0.84 | ALDH1A1 (0.69) | ALDH1A1PABPC1GSK3BMEN1KMT2A | |
| SCHEMBL1444452 | 0.83 | ALDH1A1 (0.97) | ALDH1A1PABPC1MEN1KMT2AKDM4E | |
| Bromide SCHEMBL3847335 | 0.83 | ALDH1A1 (0.72) | ALDH1A1PABPC1MEN1KMT2AKDM4E | |
| Bromide SCHEMBL4939883 | 0.83 | ALDH1A1 (0.72) | ALDH1A1PABPC1USP2MEN1KMT2A | |
| Bromide SCHEMBL2947796 | 0.83 | ALDH1A1 (0.72) | ALDH1A1PABPC1GSK3BMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2776368 | 0.82 | ALDH1A1 (0.94) | ALDH1A1PABPC1MEN1KMT2AKDM4E | |
| Bromide SCHEMBL122633 | 0.82 | ALDH1A1 (1.00) | ALDH1A1PABPC1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808163-B1 | USE OF THIAZOLIUM COMPOUNDS FOR PREVENTING AND REVERSING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS | ALTEON INC (US) | 2003-07-23 | — | — | EP | claimed |
| US-6440749-B1 | ADMINISTERING A THIAZOLE COMPOUND | ALTEON. INC. | 2002-08-27 | — | — | US | claimed |
| US-6007865-A | FOR INHIBITING AND REVERSING NONENZYMATIC CROSS-LINKING (PROTEIN AGING), TREATING KIDNEY DAMAGE AND TREATING COMPLICATIONS OF DIABETES, PREVENTING FOOD SPOILAGE | ALTEON INC. | 1999-12-28 | — | — | US | claimed |