SCHEMBL6936304

SCHEMBL6936304

C1=CC2CCC1C2.CCOC(=O)O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPM1B O75688 1/20 0.36
PTPN1 P18031 1/20 0.36
PPP1CC P36873 1/20 0.36
ALDH1A1 P00352 6/20 0.36
HSD17B10 Q99714 2/20 0.34
LMNA P02545 1/20 0.34
ALOX15 P16050 2/20 0.34
USP2 O75604 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
GAA P10253 2/20 0.33
MGAM O43451 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
SOAT1 P35610 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1477539 0.85 PPM1B (0.39) PPM1BPTPN1PPP1CCALDH1A1LMNA
Urethane SCHEMBL29060490 0.82 ALOX15 (0.58) ALDH1A1HSD17B10LMNAALOX15USP2
SCHEMBL7541604 0.80 ALDH1A1 (0.33) PPM1BPTPN1PPP1CCALDH1A1HSD17B10
SCHEMBL6537288 0.79 GAA (0.41) ALDH1A1ALOX15GAAMGAMSI
SCHEMBL1478130 0.79 MAPT (0.43)
SCHEMBL4146062 0.79 POLB (0.33) PPM1BPTPN1PPP1CCALDH1A1HSD17B10
Propionic Acid SCHEMBL943966 0.79 FFAR3 (0.48) TDP1
SCHEMBL6839066 0.77 ALDH1A1 (0.36) ALDH1A1USP2
SCHEMBL8502978 0.77 GAA (0.41) ALDH1A1HSD17B10ALOX15USP2TDP1
SCHEMBL2478423 0.76 POLB (0.32) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105126910-B A kind of C2Symmetry imidazolylphenyl rare-earth metal catalyst, preparation method and application 北京理工大学 2019-01-22 CN claimed
CN-105348415-B A kind of salicylide amido rare-earth metal catalyst, preparation method and application 北京理工大学 2019-01-11 CN claimed
CN-105348424-A Chiral half-metallocene rare earth metal catalyst, preparation method and application BEIJING INST TECHNOLOGY 2016-02-24 CN claimed
CN-105348415-A Salicylaldehyde amine-based rare earth metal catalyst, preparation method and application BEIJING INST TECHNOLOGY 2016-02-24 CN claimed
CN-107312113-B Chiral bisoxazoline cyclocarbene rare earth metal catalyst, preparation method and application 大连理工大学 2020-08-14 CN disclosed
CN-105348415-B A kind of salicylide amido rare-earth metal catalyst, preparation method and application 北京理工大学 2019-01-11 CN disclosed
CN-105348424-A Chiral half-metallocene rare earth metal catalyst, preparation method and application BEIJING INST TECHNOLOGY 2016-02-24 CN disclosed
CN-105348415-A Salicylaldehyde amine-based rare earth metal catalyst, preparation method and application BEIJING INST TECHNOLOGY 2016-02-24 CN disclosed
CN-1146620-C Processes for making polymers contg. pendant cyclic anhydride groups ס�ѵ�ľ��ʽ���� 2004-04-21 CN disclosed
US-6649714-B2 Metathesis ring opening polymerization of cyclic nonaromatic monomers, in the presence of polymerization catalysts, then hydrogenating without additional hydrogenation catalysts; efficiency SUMITOMO BAKELITE CO., LTD. (JP) 2003-11-18 US disclosed
US-20030195298-A1 Processes for making polymers containing pendant cyclic anhydride groups SUMITOMO BAKELITE CO., LTD. 2003-10-16 US disclosed
EP-1163282-B1 PROCESSES FOR MAKING POLYMERS CONTAINING PENDANT CYCLIC ANHYDRIDE GROUPS SUMITOMO BAKELITE CO (JP) 2003-05-28 EP disclosed
US-6528598-B1 E Ni(C6F5)2 and E represents a neutral electron donor; (toluene)bis(perfluorophenyl) nickel; SUMITOMO BAKELITE CO., LTD. (JP) 2003-03-04 US disclosed
US-6525153-B1 Photoresists; sensitizing photoacid initiator to longer wavelengths photolithography SUMITOMO BAKELITE CO., LTD. (JP) 2003-02-25 US disclosed
CN-1347427-A Process for preparing polymers containing cyclic anhydride pendant groups GOODRICH CO B F (US) 2002-05-01 CN disclosed
EP-1163282-A1 PROCESSES FOR MAKING POLYMERS CONTAINING PENDANT CYCLIC ANHYDRIDE GROUPS The B.F. Goodrich Company (US) 2001-12-19 EP disclosed
WO-2000053657-A1 PROCESSES FOR MAKING POLYMERS CONTAINING PENDANT CYCLIC ANHYDRIDE GROUPS THE B.F. GOODRICH COMPANY (US) 2000-09-14 WO disclosed
WO-2000053658-A1 POLYCYCLIC POLYMERS CONTAINING PENDANT CYCLIC ANHYDRIDE GROUPS THE B.F. GOODRICH COMPANY (US) 2000-09-14 WO disclosed