SCHEMBL6937289

SCHEMBL6937289

COC(=O)Oc1ccc(I)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
HSD17B10 Q99714 2/20 0.45
LMNA P02545 2/20 0.45
ALDH1A1 P00352 2/20 0.45
HTT P42858 2/20 0.45
MAPT P10636 1/20 0.45
MMP2 P08253 1/20 0.42
MMP9 P14780 1/20 0.42
MMP14 P50281 1/20 0.42
APP P05067 1/20 0.41
ELANE P08246 2/20 0.40
KDM4E B2RXH2 1/20 0.40
HPGD P15428 1/20 0.40
RAB9A P51151 1/20 0.40
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 2/20 0.39
CA12 O43570 1/20 0.39
TPMT P51580 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL676909 0.89 KMT2A (0.58) KMT2AMEN1HSD17B10LMNAALDH1A1
SCHEMBL7866352 0.86 MEN1 (0.50) KMT2AMEN1LMNAAPPELANE
SCHEMBL6936328 0.82 MMP2 (0.55) KMT2AMEN1HSD17B10LMNAALDH1A1
SCHEMBL697317 0.82 CA1 (0.56) KMT2AMEN1LMNAALDH1A1HTT
SCHEMBL8779173 0.82 KMT2A (0.52) KMT2AMEN1HSD17B10LMNAALDH1A1
SCHEMBL8830906 0.80 KMT2A (0.50) KMT2AMEN1HSD17B10LMNAALDH1A1
SCHEMBL1598492 0.80 LMNA (0.61) KMT2AMEN1HSD17B10LMNAALDH1A1
SCHEMBL24419014 0.78 KMT2A (0.52) KMT2AMEN1HSD17B10LMNAALDH1A1
SCHEMBL3946410 0.78 ALDH1A1 (0.49) KMT2AMEN1HSD17B10LMNAALDH1A1
SCHEMBL7543901 0.78 KMT2A (0.48) KMT2AMEN1HSD17B10LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4519340-B1 PROCESS FOR PREPARING A POLYCARBONATE BY METAL CATALYZED CROSS COUPLING COVESTRO DEUTSCHLAND AG (DE) 2026-04-01 EP disclosed
EP-4519340-A1 PROCESS FOR PREPARING A POLYCARBONATE BY METAL CATALYZED CROSS COUPLING Covestro Deutschland AG (DE) 2025-03-12 EP disclosed
CN-119137182-A Method for producing polycarbonates by metal-catalyzed cross-coupling 科思创德国股份有限公司 2024-12-13 CN disclosed
WO-2023213745-A1 PROCESS FOR PREPARING A POLYCARBONATE BY METAL CATALYZED CROSS COUPLING COVESTRO DEUTSCHLAND AG (DE) 2023-11-09 WO disclosed
EP-0972776-B1 A phosphine sulfide, a manufacturing process therefor and a use thereof MITSUI CHEMICALS INC (JP) 2003-04-23 EP disclosed
US-6153794-A Phosphine sulfide, a manufacturing process therefor and use thereof MITSUI CHEMICALS, INC. (JP) 2000-11-28 US disclosed
CN-1262276-A Phosphine sulfide preparing process and use thereof MITSUI CHEMICALS INC (JP) 2000-08-09 CN disclosed
EP-0972776-A1 A phosphine sulfide, a manufacturing process therefor and a use thereof Mitsui Chemicals, Inc. (JP) 2000-01-19 EP disclosed