Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 6/20 | 0.33 |
| ▸ | CTSL | P07711 | 3/20 | 0.33 |
| ▸ | CTSB | P07858 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20733126 | 0.85 | PDCD1LG2 (0.32) | TSHRLMNACTSKCTSLCTSB | |
| SCHEMBL21994867 | 0.80 | — | — | |
| SCHEMBL21676282 | 0.80 | ALDH1A1 (0.38) | TSHRLMNACYP3A4NFKB1ADRA1A | |
| SCHEMBL20186755 | 0.77 | CHRNB2 (0.41) | TSHRLMNACTSKCHRM2CHRM4 | |
| SCHEMBL28716764 | 0.75 | POLB (0.35) | TSHRLMNACTSKCTSLCTSB | |
| SCHEMBL19818898 | 0.75 | LMNA (0.32) | TSHRLMNACYP3A4NFKB1ADRA1A | |
| SCHEMBL16884458 | 0.75 | TSHR (0.59) | TSHRLMNACYP3A4NFKB1ADRA1A | |
| SCHEMBL11468912 | 0.74 | TSHR (0.38) | TSHRLMNAADRA1ACHRM2CHRM4 | |
| SCHEMBL1106982 | 0.74 | TSHR (0.46) | TSHRLMNACYP3A4NFKB1ADRA1A | |
| SCHEMBL11346817 | 0.74 | TSHR (0.38) | TSHRLMNAADRA1ACHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0992497-B1 | Manufactoring process for 1,3-Dialkyl-2-imidazolinones | MITSUI CHEMICALS INC (JP) | 2003-12-17 | — | — | EP | disclosed |
| US-6492528-B1 | 1,3-DIALKYL-2-IMIDAZOLIDINONES IN A DIRECT ONE-STEP REACTION FROM INDUSTRIALLY AVAILABLE ALKYLENE CARBONATE, N-ALKYLETHANOLAMINE OR 1,2-DIOL, WHICH CAN MINIMIZE FORMING SOLID MATERIALS AND BE READILY CONDUCTED IN AN INDUSTRIAL | MITSUI CHEMICALS, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| EP-1148052-A2 | 1,3-dialkyl-2-imidazolidinones and a manufacturing process therefor | Mitsui Chemicals, Inc. (JP) | 2001-10-24 | — | — | EP | disclosed |
| EP-1148051-A2 | 1,3-dialkyl-2-imidazolidinones and a manufacturing process therefor | Mitsui Chemicals, Inc. (JP) | 2001-10-24 | — | — | EP | disclosed |
| EP-0992497-A1 | 1,3-Dialkyl-2-imidazolidinones and a manufacturing process therefor | Mitsui Chemicals, Inc. (JP) | 2000-04-12 | — | — | EP | disclosed |