Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19810547 | 0.97 | TSHR (0.43) | TSHRHTTALOX15SMN1; SMN2HPGD | |
| Ammonia Solution, Strong SCHEMBL1930552 | 0.97 | TSHR (0.43) | TSHRHTTALOX15SMN1; SMN2HPGD | |
| SCHEMBL31650247 | 0.84 | TSHR (0.37) | TSHRHTTALOX15SMN1; SMN2HPGD | |
| SCHEMBL11744998 | 0.81 | TSHR (0.43) | TSHRHTTALOX15SMN1; SMN2HPGD | |
| SCHEMBL11544318 | 0.81 | TSHR (0.43) | TSHRHTTALOX15SMN1; SMN2HPGD | |
| SCHEMBL21676258 | 0.80 | CTSK (0.38) | TSHRHTTALOX15SMN1; SMN2HPGD | |
| SCHEMBL25082885 | 0.79 | TSHR (0.36) | TSHRHTTRAB9ACA12CA1 | |
| SCHEMBL22372338 | 0.79 | TSHR (0.41) | TSHRHTTRAB9ACA12CA1 | |
| SCHEMBL13951043 | 0.79 | TSHR (0.42) | TSHRHTTALOX15SMN1; SMN2HPGD | |
| SCHEMBL23126298 | 0.79 | TSHR (0.42) | TSHRHTTALOX15SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 602 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689704-A | The method for preparing polymer composition | 巴斯夫欧洲公司 | 2019-04-26 | — | — | CN | claimed |
| JP-4795589-B2 | — | — | 2011-10-19 | — | — | JP | claimed |
| EP-1272500-A2 | PROCESS FOR PREPARING 6-O-ALKENYL-SUBSITUTED ERYTHROMYCIN DERIVATIVES | Abbott Laboratories (US) | 2003-01-08 | — | — | EP | claimed |
| WO-2000078773-A2 | PROCESS FOR PREPARING 6-O-ALKENYL-SUBSTITUTED ERYTHROMYCIN DERIV ATIVES | ABBOTT LABORATORIES (US) | 2000-12-28 | — | — | WO | claimed |
| US-20240239828-A1 | MANNOSE 6-PHOSPHATE OR ASGPR RECEPTOR BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | US | disclosed |
| US-12037405-B2 | Anti-CD70 antibody drug conjugates | AMBRX, INC. | 2024-07-16 | — | — | US | disclosed |
| US-12037405-B2 | Anti-CD70 antibody drug conjugates | AMBRX, INC. | 2024-07-16 | — | — | US | disclosed |
| US-20240218011-A1 | GLUCOCORTICOID RECEPTOR AGONISTS AND CONJUGATES THEREOF | FIREFLY BIO, INC. | 2024-07-04 | — | — | US | disclosed |
| WO-2024049769-A2 | PATTERNED RELEASE LAYERS, AND METHODS OF MAKING AND USING THEM IN DEVICE MANUFACTURING | TERECIRCUITS CORPORATION (US) | 2024-03-07 | — | — | WO | disclosed |
| US-20240066047-A1 | ANTIBODY-DRUG CONJUGATES COMPRISING A CYCLIC DINUCLEOTIDE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-02-29 | — | — | US | disclosed |
| US-20240067642-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2024-02-29 | — | — | US | disclosed |
| US-20240072809-A1 | ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2024-02-29 | — | — | US | disclosed |
| EP-0492556-A1 | Continuous process for the preparation of isocyanates | ENICHEM SYNTHESIS S.p.A. (IT) | 1992-07-01 | — | — | EP | disclosed |
| CN-1058508-A | This new bacterial strain of mould (Drechslera) Pseudomonas of moral and contain the weed control agent of this bacterial strain and weeds control mix preparation | MITSUI TOATSU CHEMICALS (JP) | 1992-02-12 | — | — | CN | disclosed |
| EP-0311642-A4 | TEMPERATURE ADAPTABLE TEXTILE FIBERS AND METHOD OF PREPARING SAME | US COMMERCE (US) | 1991-04-24 | — | — | EP | disclosed |
| US-4908238-A | Temperature adaptable textile fibers and method of preparing same | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1990-03-13 | — | — | US | disclosed |
| US-4851291-A | Temperature adaptable textile fibers and method of preparing same | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1989-07-25 | — | — | US | disclosed |
| EP-0311642-A1 | TEMPERATURE ADAPTABLE TEXTILE FIBERS AND METHOD OF PREPARING SAME. | US COMMERCE (US) | 1989-04-19 | — | — | EP | disclosed |
| WO-1987007854-A1 | TEMPERATURE ADAPTABLE TEXTILE FIBERS AND METHOD OF PREPARING SAME | UNITED STATES OF AMERICA, REPRESENTED BY THE SECRE (US) | 1987-12-30 | — | — | WO | disclosed |
| US-4028344-A | FOAMING AGENTS, FREE RADICAL INITIATORS | PENNWALT CORPORATION (US) | 1977-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240066047-A1 | ANTIBODY-DRUG CONJUGATES COMPRISING A CYCLIC DINUCLEOTIDE | STING1, TLR9, CGAS | TSHR 2611/4885HTT 3938/4885ALOX15 2253/4885 |
| US-12037405-B2 | Anti-CD70 antibody drug conjugates | CD74, CD63, CD47 | TSHR 3236/4885HTT 2355/4885ALOX15 4277/4885 |
| US-20240218011-A1 | GLUCOCORTICOID RECEPTOR AGONISTS AND CONJUGATES THEREOF | NR3C1, NR3C2, MC2R | TSHR 179/4885HTT 3360/4885ALOX15 1205/4885 |
| US-20240239828-A1 | MANNOSE 6-PHOSPHATE OR ASGPR RECEPTOR BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | M6PR, ASGR1, IGF2R | TSHR 560/4885HTT 4400/4885ALOX15 2569/4885 |
| US-20240067642-A1 | COMPOUNDS AND USES THEREOF | VHL, TFEB, BECN1 | TSHR 4793/4885HTT 304/4885ALOX15 3136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.