Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940243 | 0.81 | FABP3 (0.39) | NR3C1GAA | |
| SCHEMBL5704723 | 0.80 | PPARG (0.33) | KAT6AMTNR1APPARA | |
| SCHEMBL5704698 | 0.77 | — | — | |
| SCHEMBL6942637 | 0.77 | PPARG (0.33) | PPARA | |
| SCHEMBL8720139 | 0.65 | FFAR4 (0.43) | KAT6APTPN1PTPN11MTNR1AMETAP2 | |
| SCHEMBL3633717 | 0.62 | FLT1 (0.34) | KAT6APTPN1PTPN11MTNR1AMETAP2 | |
| SCHEMBL1952267 | 0.62 | CA2 (0.37) | PTPN1PTPN11MTNR1AFFAR4 | |
| SCHEMBL5704754 | 0.62 | KAT6A (0.34) | KAT6AMTNR1AMETAP2PLA2G7 | |
| SCHEMBL5704708 | 0.61 | PPARG (0.34) | KAT6APTPN1PTPN11PPARA | |
| SCHEMBL11878744 | 0.61 | TTR (0.41) | KAT6AMTNR1AMETAP2NR3C1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003513909-A | — | — | 2003-04-15 | — | — | JP | claimed |
| EP-1229907-A1 | PREVENTION OF PLAQUE RUPTURE BY ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2002-08-14 | — | — | EP | claimed |
| WO-2001034127-A1 | PREVENTION OF PLAQUE RUPTURE BY ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-05-17 | — | — | WO | claimed |