Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936626 | 0.81 | KAT6A (0.33) | NR3C1GAA | |
| SCHEMBL6942637 | 0.78 | PPARG (0.33) | — | |
| SCHEMBL5704723 | 0.76 | PPARG (0.33) | — | |
| SCHEMBL6938810 | 0.74 | FABP3 (0.37) | FABP3FABP4FABP5SOAT2MYC | |
| SCHEMBL6940834 | 0.71 | FABP3 (0.44) | FABP3FABP4FABP5SOAT2MYC | |
| SCHEMBL5469738 | 0.66 | FABP3 (0.40) | FABP3FABP4FABP5SOAT2MYC | |
| SCHEMBL14519841 | 0.65 | FABP4 (0.67) | FABP3FABP4FABP5SOAT2MYC | |
| SCHEMBL5704698 | 0.64 | — | — | |
| SCHEMBL5471203 | 0.64 | NLRP3 (0.34) | — | |
| SCHEMBL21056164 | 0.63 | GABRA1 (0.41) | SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003513909-A | — | — | 2003-04-15 | — | — | JP | claimed |
| EP-1229907-A1 | PREVENTION OF PLAQUE RUPTURE BY ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2002-08-14 | — | — | EP | claimed |
| WO-2001034127-A1 | PREVENTION OF PLAQUE RUPTURE BY ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-05-17 | — | — | WO | claimed |