Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 8/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 2/20 | 0.40 |
| ▸ | CTSA | P10619 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5155595 | 0.86 | ALDH1A1 (0.44) | PTPRCCTSSCTSKALDH1A1SMN1; SMN2 | |
| SCHEMBL4167953 | 0.86 | ALDH1A1 (0.44) | PTPRCCTSSCTSKALDH1A1SMN1; SMN2 | |
| SCHEMBL16680856 | 0.86 | ALDH1A1 (0.44) | PTPRCCTSSCTSKALDH1A1SMN1; SMN2 | |
| SCHEMBL13802924 | 0.83 | GABRB1 (0.53) | CYP2D6TSHRGABRB1GABRB2UTS2R | |
| SCHEMBL5387329 | 0.82 | UTS2R (0.45) | MEN1CYP1A2CYP2D6TSHRKMT2A | |
| SCHEMBL8592999 | 0.78 | CYP2D6 (0.41) | MEN1CYP1A2CYP2D6TSHRKMT2A | |
| SCHEMBL17697851 | 0.77 | EEF2K (0.46) | CTSACTSSCTSKALDH1A1SMN1; SMN2 | |
| SCHEMBL8362256 | 0.75 | GABRB1 (0.52) | GABRB1GABRB2UTS2RCTSBCTSS | |
| SCHEMBL6359617 | 0.74 | RIPK1 (0.50) | PTPRCCTSSCTSK | |
| SCHEMBL6359621 | 0.74 | RIPK1 (0.50) | PTPRCCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907643-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2003-01-15 | — | — | EP | disclosed |
| US-5919777-A | PIPERAZINE DERIVATIVES USEFUL FOR TREATING MEDICAL DISORDERS RESULTING FROM A GROWTH HORMONE DEFIENCY | NOVO NORDISK A/S (DK) | 1999-07-06 | — | — | US | disclosed |
| EP-0907643-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1999-04-14 | — | — | EP | disclosed |
| WO-1997040023-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-10-30 | — | — | WO | disclosed |