Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 20/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 19/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 17/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7874347 | 0.99 | OPRM1 (0.44) | OPRK1OPRM1OPRD1DRD2DRD3 | |
| SCHEMBL6934080 | 0.90 | OPRK1 (0.40) | OPRK1OPRM1OPRD1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7876987 | 0.89 | OPRK1 (0.41) | OPRK1OPRM1OPRD1DRD2DRD3 | |
| SCHEMBL6934469 | 0.87 | OPRM1 (0.41) | OPRK1OPRM1OPRD1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7874351 | 0.86 | OPRM1 (0.42) | OPRK1OPRM1OPRD1DRD2DRD3 | |
| SCHEMBL6933172 | 0.82 | OPRM1 (0.38) | OPRK1OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL7870812 | 0.81 | OPRM1 (0.39) | OPRK1OPRM1OPRD1 | |
| SCHEMBL6934203 | 0.81 | OPRK1 (0.39) | OPRK1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7870761 | 0.81 | OPRK1 (0.39) | OPRK1OPRM1OPRD1DRD2DRD3 | |
| SCHEMBL6934582 | 0.79 | HRH3 (0.36) | OPRK1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1010689-B1 | Substituted cycloheptenes, their preparation and use | GRUENENTHAL GMBH (DE) | 2003-01-15 | — | — | EP | claimed |
| EP-1010689-A1 | Substituted cycloheptenes, their preparation and use | Grünenthal GmbH (DE) | 2000-06-21 | — | — | EP | claimed |
| EP-1010689-B1 | Substituted cycloheptenes, their preparation and use | GRUENENTHAL GMBH (DE) | 2003-01-15 | — | — | EP | disclosed |
| EP-1010689-A1 | Substituted cycloheptenes, their preparation and use | Grünenthal GmbH (DE) | 2000-06-21 | — | — | EP | disclosed |