Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.49 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27830162 | 0.86 | RAB9A (0.39) | CCR5ALDH1A1USP28USP25RAB9A | |
| SCHEMBL724632 | 0.85 | CCR5 (0.53) | CCR5ALDH1A1USP28USP25RAB9A | |
| SCHEMBL15148414 | 0.85 | CCR5 (0.53) | CCR5ALDH1A1USP28USP25RAB9A | |
| SCHEMBL8506775 | 0.85 | CCNB2 (0.48) | ALDH1A1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL27809813 | 0.85 | MAOB (0.41) | CCR5RAB9AHTTHTR7HTR6 | |
| SCHEMBL2166135 | 0.83 | KMT2A (0.47) | CCR5ALDH1A1USP28USP25RAB9A | |
| SCHEMBL1783943 | 0.83 | KMT2A (0.47) | CCR5ALDH1A1USP28USP25RAB9A | |
| SCHEMBL2167632 | 0.83 | KMT2A (0.47) | CCR5ALDH1A1USP28USP25RAB9A | |
| SCHEMBL12293723 | 0.82 | USP28 (0.52) | CCR5ALDH1A1USP28USP25RAB9A | |
| SCHEMBL15150708 | 0.82 | CCR5 (0.47) | CCR5ALDH1A1USP28USP25RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100482635-C | Noval compounds, their use and preparation | PFIZER HEALTH AB (SE) | 2009-04-29 | — | — | CN | disclosed |
| CN-1636967-A | Noval compounds, their use and preparation | PFIZER (SE) | 2005-07-13 | — | — | CN | disclosed |
| EP-1019358-B1 | 3,3-DIARYLPROPYLAMINES , THEIR USE AND PREPARATION | PHARMACIA AB (SE) | 2003-05-07 | — | — | EP | disclosed |
| US-6313132-B1 | FOR THERAPY OF URINARY INCONTINENCE, ACETYLCHOLINE-MEDIATED DISORDER | PHARMACIA AB (SE) | 2001-11-06 | — | — | US | disclosed |
| EP-1019358-A1 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | Pharmacia & Upjohn AB (SE) | 2000-07-19 | — | — | EP | disclosed |
| CN-1251569-A | Novel compounds, their use and process for their preparation | PHARMACIA & UPJOHN AB (SE) | 2000-04-26 | — | — | CN | disclosed |
| WO-1998043942-A1 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | PHARMACIA & UPJOHN AB (SE) | 1998-10-08 | — | — | WO | disclosed |