Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
| ▸ | USP5 | P45974 | 1/20 | 0.39 |
| ▸ | USP4 | Q13107 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31226055 | 0.87 | KMT2A (0.55) | SMN1; SMN2SENP1KMT2AALDH1A1HPGD | |
| SCHEMBL31226071 | 0.86 | SENP1 (0.61) | SMN1; SMN2SENP1CYP4F2CYP4A11KMT2A | |
| SCHEMBL31225821 | 0.84 | KMT2A (0.52) | SMN1; SMN2SENP1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL6937307 | 0.84 | SMN1; SMN2 (0.67) | SMN1; SMN2SENP1KMT2AALDH1A1HPGD | |
| SCHEMBL31225539 | 0.83 | KMT2A (0.51) | SMN1; SMN2SENP1KMT2AALDH1A1HPGD | |
| SCHEMBL31225855 | 0.81 | SMN1; SMN2 (0.44) | SMN1; SMN2SENP1CYP4F2CYP4A11KMT2A | |
| SCHEMBL5715921 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2SENP1KMT2AL3MBTL1MAPT | |
| SCHEMBL31225490 | 0.81 | SMN1; SMN2 (0.55) | SMN1; SMN2SENP1KMT2AALDH1A1UCHL1 | |
| SCHEMBL7122486 | 0.80 | L3MBTL1 (0.50) | SMN1; SMN2CYP4F2CYP4A11KMT2AALDH1A1 | |
| SCHEMBL14744261 | 0.79 | PSIP1 (0.45) | SMN1; SMN2SENP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0305929-B1 | Membranes with bound oligonucleotides and peptides | MILLIPORE CORP (US) | 1996-04-10 | — | — | EP | disclosed |
| US-5395849-A | Hybrid antitumor compounds containing a cyclic enediyne and a DNA-binder | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-03-07 | — | — | US | disclosed |
| US-4923901-A | Membranes with bound oligonucleotides and peptides | MILLIPORE CORPORATION (US) | 1990-05-08 | — | — | US | disclosed |
| EP-0305929-A2 | Membranes with bound oligonucleotides and peptides | MILLIPORE CORPORATION (US) | 1989-03-08 | — | — | EP | disclosed |