Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6941698 | 0.90 | PPOX (0.45) | PPOXGAAPKML3MBTL1TDP1 | |
| SCHEMBL6937330 | 0.88 | PTGDR2 (0.39) | PKMTDP1TSHRALDH1A1KDM4E | |
| SCHEMBL7693094 | 0.88 | LMNA (0.33) | PPOXL3MBTL1TDP1TSHRMEN1 | |
| SCHEMBL6934937 | 0.88 | LMNA (0.33) | PPOXL3MBTL1TDP1TSHRMEN1 | |
| SCHEMBL6937105 | 0.87 | KDM4E (0.36) | PPOXGAATSHRMEN1KMT2A | |
| SCHEMBL6935030 | 0.86 | PTGDR2 (0.34) | PPOXMEN1KMT2ALMNAMRGPRX4 | |
| SCHEMBL6935624 | 0.84 | PPOX (0.45) | PPOXGAAPKML3MBTL1TDP1 | |
| SCHEMBL6937364 | 0.84 | RAB9A (0.36) | PPOXLMNAMAPTALDH1A1MRGPRX4 | |
| SCHEMBL6937358 | 0.84 | RAB9A (0.36) | PPOXLMNAMAPTALDH1A1MRGPRX4 | |
| SCHEMBL7702777 | 0.83 | LMNA (0.34) | PPOXGAAL3MBTL1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1061072-B1 | Pyrrolic compounds with a high herbicidal activity and their agronomic use | ISAGRO RICERCA SRL (IT) | 2003-05-14 | — | — | EP | disclosed |
| US-6391827-B1 | CONTROLLING WEEDS | ISAGRO RICERCA S.R.L. (IT) | 2002-05-21 | — | — | US | disclosed |
| EP-1061072-A1 | Pyrrolic compounds with a high herbicidal activity and their agronomic use | ISAGRO RICERCA S.r.l. (IT) | 2000-12-20 | — | — | EP | disclosed |