SCHEMBL7702777

SCHEMBL7702777

CONC(=O)COc1cc(-c2c(Cl)c(C(F)(F)F)n(C)c2Cl)c(F)cc1Cl

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.34
GAA P10253 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
HPGD P15428 2/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
POLB P06746 1/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
NPC1 O15118 2/20 0.30
RAB9A P51151 2/20 0.30
THRB P10828 1/20 0.30
MAPK1 P28482 1/20 0.30
TSHR P16473 1/20 0.30
PPOX P50336 1/20 0.30
NFKB1 P19838 1/20 0.30
NFKB2 Q00653 1/20 0.30
RELA Q04206 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7699926 0.89 LMNA (0.33) LMNAGAASMN1; SMN2HPGDCYP1A2
SCHEMBL6937330 0.87 PTGDR2 (0.39) HPGDTSHR
SCHEMBL7693094 0.87 LMNA (0.33) LMNAMEN1KMT2AL3MBTL1TSHR
SCHEMBL6934937 0.87 LMNA (0.33) LMNAMEN1KMT2AL3MBTL1TSHR
SCHEMBL6935030 0.85 PTGDR2 (0.34) LMNAMEN1KMT2APPOX
SCHEMBL6937105 0.84 KDM4E (0.36) LMNAGAASMN1; SMN2HPGDMEN1
SCHEMBL7074077 0.84 LMNA (0.33) LMNAPPOX
SCHEMBL6935585 0.83 PPOX (0.46) LMNAGAAHPGDMEN1KMT2A
SCHEMBL7693582 0.83 POLB (0.37) LMNAGAASMN1; SMN2HPGDCYP1A2
SCHEMBL7694241 0.82 HTT (0.46) LMNAGAASMN1; SMN2HPGDPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002070476-A1 PHENYLPYRROLES WITH A HERBICIDAL ACTIVITY ISAGRO RICERCA S.R.L. (IT) 2002-09-12 WO claimed