Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7070825 | 0.90 | SLC9A1 (0.42) | SLC9A1 | |
| SCHEMBL8538237 | 0.90 | KIF18A (0.44) | SLC9A1 | |
| SCHEMBL6932987 | 0.89 | MAPT (0.44) | SLC9A1LMNAMAPTALDH1A1 | |
| SCHEMBL6932137 | 0.89 | SLC9A1 (0.48) | SLC9A1 | |
| SCHEMBL27374128 | 0.88 | MAPT (0.37) | LMNAMAPTNPSR1ALDH1A1 | |
| SCHEMBL6932480 | 0.87 | HSP90AA1 (0.40) | SLC9A1 | |
| SCHEMBL6932547 | 0.85 | SLC9A1 (0.40) | SLC9A1 | |
| SCHEMBL6938051 | 0.85 | KIF18A (0.44) | SLC9A1ALDH1A1 | |
| SCHEMBL6932460 | 0.85 | PLAU (0.39) | SLC9A1 | |
| SCHEMBL6938965 | 0.84 | SLC9A1 (0.39) | SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758644-B1 | Sulfonyl- or sulfinyl-benzoyl-guanidine derivatives | MERCK PATENT GMBH (DE) | 2003-10-15 | — | — | EP | disclosed |
| US-5744641-A | Sulfonyl- or sulfinylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-28 | — | — | US | disclosed |
| EP-0758644-A1 | Sulfonyl- or sulfinyl-benzoyl-guanidine derivatives | MERCK PATENT GmbH (DE) | 1997-02-19 | — | — | EP | disclosed |