Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.40 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 3/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937615 | 0.91 | HPD (0.37) | SLC9A1 | |
| SCHEMBL6936292 | 0.89 | SLC9A1 (0.44) | HSP90AA1CXCR5APLNRCCR6SLC9A1 | |
| SCHEMBL6937331 | 0.87 | SLC9A1 (0.40) | SLC9A1 | |
| SCHEMBL8538237 | 0.86 | KIF18A (0.44) | SLC9A1 | |
| SCHEMBL6932987 | 0.86 | MAPT (0.44) | SLC9A1 | |
| SCHEMBL6936878 | 0.85 | SLC9A1 (0.41) | SLC9A1MMP1MMP2MMP9MMP8 | |
| SCHEMBL6935267 | 0.85 | SLC9A1 (0.46) | SLC9A1 | |
| SCHEMBL6937447 | 0.83 | SLC9A1 (0.39) | SLC9A1 | |
| SCHEMBL7070825 | 0.82 | SLC9A1 (0.42) | SLC9A1 | |
| SCHEMBL6938051 | 0.81 | KIF18A (0.44) | SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758644-B1 | Sulfonyl- or sulfinyl-benzoyl-guanidine derivatives | MERCK PATENT GMBH (DE) | 2003-10-15 | — | — | EP | disclosed |
| US-5744641-A | Sulfonyl- or sulfinylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-28 | — | — | US | disclosed |
| EP-0758644-A1 | Sulfonyl- or sulfinyl-benzoyl-guanidine derivatives | MERCK PATENT GmbH (DE) | 1997-02-19 | — | — | EP | disclosed |