Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937153 | 0.85 | ALDH1A1 (0.33) | L3MBTL1ALDH1A1TDP1TSHRPOLB | |
| SCHEMBL6940069 | 0.76 | TDP1 (0.37) | L3MBTL1ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL6939766 | 0.74 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1TSHRMAPK1NPSR1 | |
| SCHEMBL6939406 | 0.70 | ALDH1A1 (0.55) | L3MBTL1ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL8108103 | 0.65 | LMNA (0.40) | L3MBTL1ALDH1A1TDP1TSHR | |
| SCHEMBL6932370 | 0.64 | ALDH1A1 (0.33) | ALDH1A1HTT | |
| SCHEMBL6937570 | 0.62 | ALDH1A1 (0.41) | L3MBTL1ALDH1A1TSHRMAPK1 | |
| SCHEMBL1459442 | 0.60 | — | — | |
| SCHEMBL6939446 | 0.59 | ALDH1A1 (0.38) | L3MBTL1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL6939159 | 0.59 | MAPT (0.42) | L3MBTL1ALDH1A1TDP1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1058681-B1 | NOVEL ALLYLTHIOPYRIDAZINE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | SEOUL PHARM CO LTD (KR) | 2003-05-07 | — | — | EP | disclosed |
| EP-1058681-A1 | NOVEL ALLYLTHIOPYRIDAZINE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | Seoul Pharm. Co., Ltd. (KR) | 2000-12-13 | — | — | EP | disclosed |
| US-5942511-A | PROTECTION OF HUMAN TISSUE FROM RADIATION | Kwon, Soon Kyoung (KR) | 1999-08-24 | — | — | US | disclosed |
| WO-1999036407-A1 | NOVEL ALLYLTHIOPYRIDAZINE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | SEOUL PHARM. CO., LTD. (KR) | 1999-07-22 | — | — | WO | disclosed |