SCHEMBL6937153

SCHEMBL6937153

C=CCSc1nnc(OCC)c2c1CCCC2

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
TSHR P16473 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
POLB P06746 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6937349 0.85 L3MBTL1 (0.35) ALDH1A1TSHRTDP1L3MBTL1POLB
SCHEMBL6937570 0.76 ALDH1A1 (0.41) ALDH1A1TSHRL3MBTL1SMN1; SMN2
SCHEMBL6940069 0.74 TDP1 (0.37) ALDH1A1TSHRTDP1L3MBTL1
SCHEMBL6939159 0.71 MAPT (0.42) ALDH1A1TSHRTDP1L3MBTL1POLB
SCHEMBL6934987 0.68 GLA (0.36) ALDH1A1TSHRPOLB
SCHEMBL6939766 0.63 ALDH1A1 (0.40) ALDH1A1TSHRL3MBTL1SMN1; SMN2
SCHEMBL8108103 0.63 LMNA (0.40) ALDH1A1TSHRTDP1L3MBTL1
SCHEMBL8094229 0.62 ALDH1A1 (0.39) ALDH1A1TSHRL3MBTL1SMN1; SMN2
SCHEMBL6937102 0.61 RAB9A (0.40) ALDH1A1TSHRL3MBTL1SMN1; SMN2
SCHEMBL6939406 0.59 ALDH1A1 (0.55) ALDH1A1TDP1L3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1058681-B1 NOVEL ALLYLTHIOPYRIDAZINE DERIVATIVES AND PROCESS FOR PREPARING THE SAME SEOUL PHARM CO LTD (KR) 2003-05-07 EP disclosed
EP-1058681-A1 NOVEL ALLYLTHIOPYRIDAZINE DERIVATIVES AND PROCESS FOR PREPARING THE SAME Seoul Pharm. Co., Ltd. (KR) 2000-12-13 EP disclosed
US-5942511-A PROTECTION OF HUMAN TISSUE FROM RADIATION Kwon, Soon Kyoung (KR) 1999-08-24 US disclosed
WO-1999036407-A1 NOVEL ALLYLTHIOPYRIDAZINE DERIVATIVES AND PROCESS FOR PREPARING THE SAME SEOUL PHARM. CO., LTD. (KR) 1999-07-22 WO disclosed