Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD5 | P21918 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6938648 | 0.84 | RAB9A (0.42) | KDM4EMEN1KMT2A | |
| SCHEMBL6939698 | 0.83 | NPC1 (0.44) | KDM4EMEN1KMT2A | |
| SCHEMBL6940552 | 0.82 | NPC1 (0.41) | KDM4EMEN1KMT2A | |
| SCHEMBL6940340 | 0.81 | L3MBTL1 (0.36) | KDM4EMEN1KMT2A | |
| SCHEMBL6937102 | 0.81 | RAB9A (0.40) | KDM4EMEN1KMT2A | |
| SCHEMBL6940557 | 0.81 | ACACB (0.40) | MEN1KMT2A | |
| SCHEMBL6939446 | 0.79 | ALDH1A1 (0.38) | KDM4EMEN1KMT2A | |
| Dimethylamine SCHEMBL6937545 | 0.77 | RAB9A (0.38) | KDM4EMEN1KMT2A | |
| SCHEMBL6940408 | 0.74 | ACACB (0.36) | MEN1KMT2A | |
| SCHEMBL6942005 | 0.74 | RAB9A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1058681-B1 | NOVEL ALLYLTHIOPYRIDAZINE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | SEOUL PHARM CO LTD (KR) | 2003-05-07 | — | — | EP | disclosed |
| EP-1058681-A1 | NOVEL ALLYLTHIOPYRIDAZINE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | Seoul Pharm. Co., Ltd. (KR) | 2000-12-13 | — | — | EP | disclosed |
| US-5942511-A | PROTECTION OF HUMAN TISSUE FROM RADIATION | Kwon, Soon Kyoung (KR) | 1999-08-24 | — | — | US | disclosed |
| WO-1999036407-A1 | NOVEL ALLYLTHIOPYRIDAZINE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | SEOUL PHARM. CO., LTD. (KR) | 1999-07-22 | — | — | WO | disclosed |