Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL6937545 | 0.95 | RAB9A (0.38) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6938648 | 0.88 | RAB9A (0.42) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6939698 | 0.86 | NPC1 (0.44) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6940552 | 0.85 | NPC1 (0.41) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6939446 | 0.85 | ALDH1A1 (0.38) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6940340 | 0.81 | L3MBTL1 (0.36) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6940557 | 0.81 | ACACB (0.40) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6937541 | 0.81 | HTR7 (0.38) | KDM4EMEN1KMT2A | |
| SCHEMBL6940408 | 0.79 | ACACB (0.36) | RAB9ANPC1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL6942005 | 0.79 | RAB9A (0.33) | RAB9ANPC1ALDH1A1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1058681-B1 | NOVEL ALLYLTHIOPYRIDAZINE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | SEOUL PHARM CO LTD (KR) | 2003-05-07 | — | — | EP | disclosed |