Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MMP8 | P22894 | 2/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31411073 | 0.83 | BTN3A1 (0.35) | HTTRCE1ALDH1A1LMNAHPGD | |
| SCHEMBL15539656 | 0.81 | TRPA1 (0.38) | TRPA1 | |
| SCHEMBL15540392 | 0.81 | TRPA1 (0.38) | TRPA1 | |
| SCHEMBL4197217 | 0.78 | ALDH1A1 (0.39) | ALDH1A1BTN3A1KMT2AMAPT | |
| SCHEMBL23768525 | 0.77 | CA1 (0.52) | HTTTSHRMAPK1KMT2A | |
| SCHEMBL23867732 | 0.77 | BTN3A1 (0.36) | RCE1BTN3A1 | |
| SCHEMBL27032528 | 0.76 | DUT (0.37) | HTTALDH1A1LMNAHPGDTSHR | |
| SCHEMBL877597 | 0.76 | BTN3A1 (0.43) | ALDH1A1LMNATSHRMAPK1BTN3A1 | |
| SCHEMBL27131617 | 0.76 | DUT (0.37) | HTTALDH1A1LMNAHPGDTSHR | |
| SCHEMBL17093259 | 0.76 | RIPK1 (0.39) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596738-B1 | Inhibiting activity to adenosine deaminase (hereinafter described as ADA) An adenosine deaminase inhibiting agent comprising a compound of the formula (I): | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-22 | — | — | US | disclosed |