SCHEMBL6937659

SCHEMBL6937659

c1ccc(SN2CN(Sc3ccccc3)CN(Sc3ccccc3)C2)cc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.43
HSD17B10 Q99714 2/20 0.43
HPGD P15428 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
MGLL Q99685 1/20 0.43
ALDH1A1 P00352 2/20 0.39
MAPK1 P28482 1/20 0.38
MAOA P21397 2/20 0.34
MAOB P27338 2/20 0.34
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
SIGMAR1 Q99720 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
FFAR1 O14842 1/20 0.31
CHRNA7 P36544 1/20 0.31
HTR1A P08908 1/20 0.31
HTR3A P46098 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2058891 0.79 ALDH1A1 (0.50) MAPTHSD17B10HPGDSMN1; SMN2MGLL
SCHEMBL4872049 0.77 ALDH1A1 (0.53) MAPTHSD17B10HPGDSMN1; SMN2MGLL
Hydrochloric Acid SCHEMBL29995407 0.75 ALDH1A1 (0.52) MAPTHSD17B10HPGDSMN1; SMN2MGLL
SCHEMBL11766841 0.74 HTR1A (0.49) MEN1KMT2ASIGMAR1HTR1AHTR3A
SCHEMBL9579555 0.74 MAPT (0.49) MAPTHSD17B10HPGDSMN1; SMN2MGLL
SCHEMBL16971310 0.72 MEN1 (0.50) MAPTHSD17B10HPGDSMN1; SMN2MGLL
SCHEMBL15082071 0.72 LMNA (0.52) MAPTHSD17B10HPGDSMN1; SMN2MGLL
SCHEMBL4134087 0.71 MAPT (0.40) MAPTHSD17B10HPGDSMN1; SMN2MGLL
SCHEMBL21117789 0.71 NPC1 (0.44) MAPTHSD17B10SMN1; SMN2ALDH1A1SIGMAR1
SCHEMBL24194726 0.69 S1PR5 (0.44) MAPTSMN1; SMN2KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030085387-A1 Optical materials and optical part each containing aromatic sulfide compound and aromatic sulfide compound MITSUI CHEMICALS, INC. (JP) 2003-05-08 US disclosed
EP-1291679-A1 OPTICAL MATERIAL AND OPTICAL PART EACH CONTAINING AROMATIC SULFIDE COMPOUND AND AROMATIC SULFIDE COMPOUND Mitsui Chemicals, Inc. (JP) 2003-03-12 EP disclosed