Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL2945063 | 0.99 | ALDH1A1 (0.45) | ALDH1A1KMT2AGSK3BMAPTSMN1; SMN2 | |
| Bromide SCHEMBL4078658 | 0.95 | ALDH1A1 (0.42) | ALDH1A1KMT2AGSK3BMAPTSMN1; SMN2 | |
| SCHEMBL6936500 | 0.85 | GSK3A (0.44) | ALDH1A1KMT2AGSK3BMAPTSMN1; SMN2 | |
| Bromide SCHEMBL3963512 | 0.84 | GSK3A (0.43) | ALDH1A1KMT2AGSK3BMAPTSMN1; SMN2 | |
| SCHEMBL6938200 | 0.73 | ALDH1A1 (0.49) | ALDH1A1KMT2AGSK3BMAPTSMN1; SMN2 | |
| SCHEMBL6935144 | 0.73 | GSK3B (0.44) | ALDH1A1KMT2AGSK3BMAPTSMN1; SMN2 | |
| Bromide SCHEMBL3851561 | 0.72 | MAPT (0.50) | ALDH1A1KMT2AGSK3BMAPTSMN1; SMN2 | |
| Bromide SCHEMBL2947798 | 0.72 | RAB9A (0.46) | ALDH1A1KMT2AGSK3BMAPTSMN1; SMN2 | |
| SCHEMBL4255420 | 0.71 | MAPT (0.48) | ALDH1A1KMT2AGSK3BMAPTSMN1; SMN2 | |
| SCHEMBL28841430 | 0.70 | ALDH1A1 (0.48) | ALDH1A1KMT2AGSK3BMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808163-B1 | USE OF THIAZOLIUM COMPOUNDS FOR PREVENTING AND REVERSING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS | ALTEON INC (US) | 2003-07-23 | — | — | EP | claimed |
| US-6440749-B1 | ADMINISTERING A THIAZOLE COMPOUND | ALTEON. INC. | 2002-08-27 | — | — | US | claimed |