Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 4/20 | 0.38 |
| ▸ | METAP1 | P53582 | 2/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.36 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 3/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSH | P09668 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3666308 | 0.82 | CCR1 (0.37) | KMT2AMETAP2METAP1CPB2CTSK | |
| SCHEMBL1859132 | 0.81 | CTSK (0.40) | KMT2ACPB2CTSKCTSSBCHE | |
| SCHEMBL969488 | 0.80 | CPB2 (0.36) | ALDH1A1METAP2METAP1CPB2CTSK | |
| SCHEMBL1865571 | 0.80 | CTSK (0.40) | CTSKCTSSLTA4HCTSLCTSB | |
| SCHEMBL970649 | 0.77 | CTSK (0.36) | CPB2CTSKCTSSBCHECTSL | |
| SCHEMBL972385 | 0.77 | CTSK (0.36) | CPB2CTSKCTSSBCHECTSL | |
| SCHEMBL6938465 | 0.76 | CTSK (0.43) | CPB2CTSKCTSSCTSLCTSB | |
| SCHEMBL7300069 | 0.73 | CTSK (0.33) | CTSKCTSSCTSLCTSBCTSH | |
| SCHEMBL6477996 | 0.71 | METAP2 (0.59) | ALDH1A1KMT2AMETAP2METAP1REN | |
| SCHEMBL6477560 | 0.71 | METAP2 (0.59) | ALDH1A1KMT2AMETAP2METAP1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272456-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | Abbott Laboratories (US) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001079157-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-10-25 | — | — | WO | disclosed |