Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSH | P09668 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1859132 | 0.80 | CTSK (0.40) | CTSKCTSLCTSBCTSHCTSS | |
| SCHEMBL969488 | 0.76 | CPB2 (0.36) | CTSKCTSLCTSBCTSHCTSS | |
| SCHEMBL970649 | 0.76 | CTSK (0.36) | CTSKCTSLCTSBCTSHCTSS | |
| SCHEMBL972385 | 0.76 | CTSK (0.36) | CTSKCTSLCTSBCTSHCTSS | |
| SCHEMBL1865571 | 0.76 | CTSK (0.40) | CTSKCTSLCTSBCTSHCTSS | |
| SCHEMBL6938465 | 0.75 | CTSK (0.43) | CTSKCTSLCTSBCTSHCTSS | |
| SCHEMBL970772 | 0.75 | CTSK (0.36) | CTSKCTSLCTSBCTSHCTSS | |
| SCHEMBL969953 | 0.75 | CTSK (0.36) | CTSKCTSLCTSBCTSHCTSS | |
| SCHEMBL6938463 | 0.73 | ALDH1A1 (0.41) | CTSKCTSLCTSBCTSHCTSS | |
| SCHEMBL7309227 | 0.73 | BCHE (0.33) | CTSKCTSLCTSBCTSHCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5189023-A | Hypotensive agent | AMERICAN CYANAMID COMPANY (US) | 1993-02-23 | — | — | US | disclosed |
| EP-0473936-A1 | Renin Inhibitors | AMERICAN CYANAMID COMPANY (US) | 1992-03-11 | — | — | EP | disclosed |