Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16688501 | 0.86 | ALOX15 (0.47) | HSD17B10ALOX15ALOX12HPGDTSHR | |
| SCHEMBL12245506 | 0.86 | ALOX15 (0.47) | HSD17B10ALOX15ALOX12HPGDTSHR | |
| SCHEMBL12960518 | 0.84 | LMNA (0.36) | HSD17B10ALOX15ALOX12HPGDTSHR | |
| SCHEMBL6939287 | 0.81 | HSD17B10 (0.50) | HSD17B10ALOX15ALOX12HPGDTSHR | |
| SCHEMBL27601386 | 0.81 | HSD17B10 (0.52) | HSD17B10ALOX15ALOX12HPGDTSHR | |
| SCHEMBL25874933 | 0.80 | RXRA (0.36) | HSD17B10HPGDTSHRALDH1A1HIF1A | |
| SCHEMBL10886229 | 0.80 | HSD17B10 (0.42) | HSD17B10ALOX15ALOX12HPGDTSHR | |
| SCHEMBL10404848 | 0.80 | HSD17B10 (0.48) | HSD17B10ALOX15ALOX12HPGDTSHR | |
| SCHEMBL14580012 | 0.79 | HPGD (0.44) | HSD17B10ALOX15ALOX12HPGDTSHR | |
| SCHEMBL12245504 | 0.79 | ALDH1A1 (0.41) | HSD17B10ALOX15ALOX12HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972776-B1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | MITSUI CHEMICALS INC (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6153794-A | Phosphine sulfide, a manufacturing process therefor and use thereof | MITSUI CHEMICALS, INC. (JP) | 2000-11-28 | — | — | US | disclosed |
| EP-0972776-A1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | Mitsui Chemicals, Inc. (JP) | 2000-01-19 | — | — | EP | disclosed |