Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935891 | 0.86 | — | — | |
| SCHEMBL6937720 | 0.85 | GRIN2D (0.37) | KDM4EALDH1A1HPGD | |
| SCHEMBL6928527 | 0.80 | PARP1 (0.40) | — | |
| SCHEMBL7735087 | 0.78 | NTRK1 (0.35) | KDM4EALDH1A1GLAGAAHPGD | |
| Nitrogen SCHEMBL27548156 | 0.77 | CDK5 (0.36) | — | |
| SCHEMBL7068983 | 0.77 | PARP1 (0.43) | GAA | |
| SCHEMBL6928804 | 0.77 | TRPV4 (0.31) | — | |
| SCHEMBL6923612 | 0.77 | CA1 (0.36) | KDM4EALDH1A1POLB | |
| SCHEMBL7740361 | 0.76 | GRIA1 (0.54) | — | |
| SCHEMBL7648893 | 0.75 | TAS2R14 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1125940-B1 | Derivatives of aryl or heteroaryl quinolinylphosphonic acids, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-01-15 | — | — | EP | disclosed |
| US-6420386-B1 | SPINAL TRAUMATISM, EPILEPSY, CHRONIC NEURODEGENERATIVE DISEASES SUCH AS ALZHEIMER'S DISEASE, SCHIZOPHRENIA, LATERAL AMYOTROPHIC SCLEROSIS OR HUNTINGTON'S CHOREA. | LES LABORATORIES SERVIER (FR) | 2002-07-16 | — | — | US | disclosed |
| CN-1317489-A | Novel aryl radical or heteroaryl radical quinolyl phosphonate compounds, its preparing method and medical compsn. contg. them | ADIR (FR) | 2001-10-17 | — | — | CN | disclosed |
| EP-1125940-A1 | Derivatives of aryl or heteroaryl quinolinylphosphonic acids, process for their preparation and pharmaceutical compositions containing them | Adir Et Cie (FR) | 2001-08-22 | — | — | EP | disclosed |