Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 2/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3232439 | 0.86 | ALDH1A1 (0.47) | L3MBTL1LMNATSHRGAAALDH1A1 | |
| SCHEMBL13742168 | 0.84 | MAPT (0.41) | L3MBTL1CRHBPCRHR2CYP1A2SIGMAR1 | |
| SCHEMBL4031971 | 0.81 | CA2 (0.51) | TDP1LMNAPOLBTSHRGAA | |
| SCHEMBL6936444 | 0.74 | MAPT (0.36) | LMNAHTTTSHRALDH1A1MAPT | |
| SCHEMBL7904922 | 0.71 | ALDH1A1 (0.45) | L3MBTL1LMNATSHRGAAALDH1A1 | |
| SCHEMBL3483627 | 0.70 | ALDH1A1 (0.40) | TDP1POLBHSP90AA1HTTALDH1A1 | |
| SCHEMBL11074404 | 0.69 | PDE7A (0.46) | LMNAHTTTSHRALOX15ALDH1A1 | |
| SCHEMBL4102194 | 0.68 | LMNA (0.59) | L3MBTL1TDP1LMNAPOLBCYP1A2 | |
| SCHEMBL2970186 | 0.68 | ALDH1A1 (0.47) | L3MBTL1LMNAHTTTSHRGAA | |
| SCHEMBL1865811 | 0.67 | ALDH1A1 (0.53) | LMNATSHRGAAALDH1A1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888278-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2003-07-23 | — | — | EP | disclosed |