Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | LPO | P22079 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3848581 | 0.99 | ALDH1A1 (0.45) | ALDH1A1KDM4ESIGMAR1CMA1LPO | |
| SCHEMBL4252730 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KDM4ESIGMAR1MAPTTHRB | |
| Hydrochloric Acid SCHEMBL313570 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KDM4ESIGMAR1MAPTTHRB | |
| Bromide SCHEMBL3846883 | 0.78 | CA12 (0.45) | ALDH1A1KDM4EMAPTTP53 | |
| SCHEMBL31081822 | 0.72 | SIGMAR1 (0.52) | ALDH1A1KDM4ESIGMAR1CMA1LPO | |
| SCHEMBL43521 | 0.72 | TAAR1 (0.67) | SIGMAR1HRH3TAAR1 | |
| Alcohol SCHEMBL5332610 | 0.69 | TAAR1 (0.62) | SIGMAR1HRH3TAAR1 | |
| Hydrochloric Acid SCHEMBL648278 | 0.68 | SIRT2 (0.36) | SIGMAR1SIRT2SIRT1 | |
| SCHEMBL27298114 | 0.67 | SIGMAR1 (0.73) | ALDH1A1KDM4ESIGMAR1PKMHRH3 | |
| SCHEMBL81474 | 0.66 | CHRM2 (0.63) | SIGMAR1HDAC1HDAC6HRH3TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808163-B1 | USE OF THIAZOLIUM COMPOUNDS FOR PREVENTING AND REVERSING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS | ALTEON INC (US) | 2003-07-23 | — | — | EP | claimed |
| US-6440749-B1 | ADMINISTERING A THIAZOLE COMPOUND | ALTEON. INC. | 2002-08-27 | — | — | US | claimed |