Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.63 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.63 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.62 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.60 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.56 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | AGXT | P21549 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23266720 | 0.95 | CHRM2 (0.61) | CHRM2CHRM1CHRM3TAAR1MTNR1A | |
| SCHEMBL17274721 | 0.93 | HDAC1 (0.62) | CHRM2CHRM1CHRM3TAAR1MTNR1A | |
| SCHEMBL15746740 | 0.93 | HDAC1 (0.62) | CHRM2CHRM1CHRM3TAAR1MTNR1A | |
| SCHEMBL7743344 | 0.90 | BACE1 (0.55) | CHRM2CHRM1CHRM3TAAR1MTNR1A | |
| SCHEMBL43521 | 0.89 | TAAR1 (0.67) | CHRM2CHRM1CHRM3TAAR1MTNR1A | |
| SCHEMBL29986862 | 0.88 | TAAR1 (0.71) | CHRM2CHRM1CHRM3TAAR1MTNR1A | |
| SCHEMBL21002162 | 0.88 | TAAR1 (0.71) | CHRM2CHRM1CHRM3TAAR1MTNR1A | |
| SCHEMBL21002016 | 0.88 | TAAR1 (0.71) | CHRM2CHRM1CHRM3TAAR1MTNR1A | |
| SCHEMBL21002124 | 0.86 | TAAR1 (0.69) | CHRM2CHRM1CHRM3TAAR1MTNR1A | |
| Alcohol SCHEMBL5332610 | 0.85 | TAAR1 (0.62) | CHRM2CHRM1CHRM3TAAR1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1309723-C | Method for producing optically active salicylaldimine copper complex | SUMITOMO CHEMICAL CO (JP) | 2007-04-11 | — | — | CN | claimed |
| EP-3782996-B1 | NRF2 REGULATORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2024-04-10 | — | — | EP | disclosed |
| CN-111971277-B | Benzothiophenes and related compounds as STING agonists | 默沙东有限责任公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-109879852-B | Naphthopyran branched triptycene compound, preparation method and application thereof | 上海甘田光学材料有限公司 | 2023-05-30 | — | — | CN | disclosed |
| US-20230047296-A1 | Nrf2 REGULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-02-16 | — | — | US | disclosed |
| US-20230047296-A1 | Nrf2 REGULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-02-16 | — | — | US | disclosed |
| CN-115385782-A | Mechanochemical synthesis method of benzoyl compound | 兰州大学 | 2022-11-25 | — | — | CN | disclosed |
| CN-110407739-B | Preparation method of (4, 6-diaryl-tetrahydropyridine-3-yl) (aryl) ketone | 上海应用技术大学 | 2021-09-28 | — | — | CN | disclosed |
| CN-113264865-A | 2-amino-4-benzoyl-4, 5-dihydro-1H-pyrrole-3-carbon nitrile and preparation method thereof | 上海应用技术大学 | 2021-08-17 | — | — | CN | disclosed |
| US-11001575-B1 | Benzolactam compounds as protein kinase inhibitors | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2021-05-11 | — | — | US | disclosed |
| US-5541228-A | Melatonergic agents | BRISTOL-MYERS SQUIBB CO. (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0706994-A1 | Melatonergic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-04-17 | — | — | EP | disclosed |
| EP-0162208-B1 | NOVEL N-SUBSTITUTED 3,4-DIHYDROPYRIMIDINE DERIVATIVES, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS | SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD. (JP) | 1989-11-23 | — | — | EP | disclosed |
| US-4683234-A | HYPOTENSIVE AGENTS, ANTI-ANGINA | SUNTORY LIMITED (JP) | 1987-07-28 | — | — | US | disclosed |
| US-4618683-A | Tetrahydro-6,7-dimethoxy-1H-benz[e]isoinodolines useful in the treatment of hypertension and as sedatives | ABBOTT LABORATORIES (US) | 1986-10-21 | — | — | US | disclosed |
| EP-0162208-A2 | Novel N-substituted 3,4-dihydropyrimidine derivatives, processes for preparing them and pharmaceutical compositions | SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD. (JP) | 1985-11-27 | — | — | EP | disclosed |
| US-3989723-A | ANTICOCCIDIAL, INSECTICIDES, ACARICIDES | ELI LILLY AND COMPANY (US) | 1976-11-02 | — | — | US | disclosed |
| US-3979458-A | Production of unsaturated carbocyclic ketones | SYNTEX CORPORATION (PM) | 1976-09-07 | — | — | US | disclosed |
| US-3959322-A | Synthesis of 13-alkyl-gon-4-ones | Smith, Herchel (US) | 1976-05-25 | — | — | US | disclosed |
| US-3953474-A | ANTICOCCIDIAL, ANTIMICROBIAL | ELI LILLY AND COMPANY (US) | 1976-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230047296-A1 | Nrf2 REGULATORS | NFE2L2, KEAP1, NQO1 | CHRM2 3703/4885CHRM1 3946/4885CHRM3 3292/4885 |
| US-11001575-B1 | Benzolactam compounds as protein kinase inhibitors | MAPK1, ALK, MAP3K1 | CHRM2 651/4885CHRM1 209/4885CHRM3 1221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.