Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.55 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.52 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8062302 | 0.89 | MEN1 (0.60) | MEN1KMT2ARXFP1ALDH1A1KCNK3 | |
| SCHEMBL3914853 | 0.87 | PLAU (0.62) | MEN1KMT2APOLBNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL3922301 | 0.86 | PLAU (0.61) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL20848006 | 0.82 | NPC1 (0.78) | MEN1KMT2ARXFP1ALDH1A1KCNK3 | |
| SCHEMBL7047835 | 0.81 | PLAU (0.59) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL8506194 | 0.81 | MEN1 (0.69) | MEN1KMT2AALDH1A1POLBNPC1 | |
| SCHEMBL24332744 | 0.81 | SRC (0.80) | MEN1KMT2ARXFP1ALDH1A1POLB | |
| SCHEMBL6575251 | 0.80 | PLAU (0.64) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL2743105 | 0.80 | KMT2A (0.74) | MEN1KMT2AALDH1A1POLBNPC1 | |
| SCHEMBL13220719 | 0.79 | MEN1 (0.68) | MEN1KMT2ARXFP1ALDH1A1KCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882705-B1 | BIS(AMINOCARBONYLNAPHTHOL) DERIVATIVE | UENO SEIYAKU OYO KENKYUJO KK (JP) | 2003-05-28 | — | — | EP | disclosed |
| US-6072042-A | Bis(aminocarbonylnaphthol) derivative | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2000-06-06 | — | — | US | disclosed |
| EP-0882705-A1 | BIS(AMINOCARBONYLNAPHTHOL) DERIVATIVE | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1998-12-09 | — | — | EP | disclosed |