Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 3/20 | 0.59 |
| ▸ | PLG | P00747 | 3/20 | 0.56 |
| ▸ | F2 | P00734 | 2/20 | 0.56 |
| ▸ | PLAT | P00750 | 2/20 | 0.56 |
| ▸ | KLK1 | P06870 | 2/20 | 0.56 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
| ▸ | F10 | P00742 | 1/20 | 0.53 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
| ▸ | GPR39 | O43194 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3914853 | 0.94 | PLAU (0.62) | PLAUPLGF2PLATKLK1 | |
| SCHEMBL8480342 | 0.93 | PLAU (0.62) | PLAUPLGF2PLATKLK1 | |
| Hydrochloric Acid SCHEMBL3922301 | 0.92 | PLAU (0.61) | PLAUPLGF2PLATKLK1 | |
| SCHEMBL6575251 | 0.87 | PLAU (0.64) | PLAUPLGF2PLATKLK1 | |
| SCHEMBL8485202 | 0.86 | PLG (0.58) | PLAUPLGF2PLATKLK1 | |
| SCHEMBL8484998 | 0.85 | SRC (0.58) | PLAUPLGF2PLATKLK1 | |
| SCHEMBL3922289 | 0.83 | PLAU (0.59) | PLAUPLGF2PLATKLK1 | |
| SCHEMBL3925183 | 0.83 | PLG (0.62) | PLAUPLGF2PLATKLK1 | |
| Hydrochloric Acid SCHEMBL3922499 | 0.82 | PLG (0.61) | PLAUPLGF2PLATKLK1 | |
| SCHEMBL6938709 | 0.81 | MEN1 (0.58) | PTPN11KMT2ASRCNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882767-B1 | BISAZO COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | UENO SEIYAKU OYO KENKYUJO KK (JP) | 2003-04-16 | — | — | EP | disclosed |
| EP-0882767-A1 | BISAZO COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1998-12-09 | — | — | EP | disclosed |