Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 2/20 | 0.37 |
| ▸ | FABP4 | P15090 | 2/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.31 |
| ▸ | MYC | P01106 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5469738 | 0.83 | FABP3 (0.40) | FABP3FABP4FABP5GAASOAT2 | |
| SCHEMBL5704723 | 0.79 | PPARG (0.33) | — | |
| SCHEMBL5704698 | 0.79 | — | — | |
| SCHEMBL6940243 | 0.74 | FABP3 (0.39) | FABP3FABP4FABP5GAASOAT2 | |
| SCHEMBL5471203 | 0.71 | NLRP3 (0.34) | — | |
| SCHEMBL8706010 | 0.65 | FABP3 (0.38) | FABP3FABP4FABP5GAASOAT2 | |
| SCHEMBL7104863 | 0.62 | FABP3 (0.40) | FABP3FABP4FABP5GAA | |
| SCHEMBL7108814 | 0.60 | FABP3 (0.41) | FABP3FABP4FABP5GAA | |
| SCHEMBL8720137 | 0.59 | FABP4 (0.58) | FABP3FABP4FABP5GAASOAT2 | |
| SCHEMBL6936626 | 0.59 | KAT6A (0.33) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003513909-A | — | — | 2003-04-15 | — | — | JP | claimed |
| EP-1229907-A1 | PREVENTION OF PLAQUE RUPTURE BY ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2002-08-14 | — | — | EP | claimed |
| WO-2001034127-A1 | PREVENTION OF PLAQUE RUPTURE BY ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-05-17 | — | — | WO | claimed |