Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6939365 | 0.83 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2TSHRKMT2A | |
| SCHEMBL6935736 | 0.82 | CNR2 (0.37) | ALDH1A1NPSR1KDM4ESMN1; SMN2POLB | |
| SCHEMBL6941415 | 0.80 | CA9 (0.47) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6934329 | 0.79 | CA9 (0.46) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6934342 | 0.78 | L3MBTL1 (0.40) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2POLB | |
| SCHEMBL6937780 | 0.77 | ALDH1A1 (0.41) | ALDH1A1VCAM1KDM4ESMN1; SMN2POLB | |
| SCHEMBL6939756 | 0.77 | GRIN2D (0.33) | ALDH1A1KDM4ESMN1; SMN2HSD17B10TSHR | |
| SCHEMBL6942103 | 0.76 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2POLBTSHRKMT2A | |
| SCHEMBL6938296 | 0.76 | CA1 (0.42) | L3MBTL1SMN1; SMN2POLBHSD17B10TSHR | |
| SCHEMBL7652678 | 0.75 | KDM4E (0.38) | ALDH1A1NPSR1L3MBTL1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1125942-B1 | Derivatives of 6-amino or 6-hydrazinosulfonyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-09 | — | — | EP | disclosed |
| EP-1125942-A1 | Derivatives of 6-amino or 6-hydrazinosulfonyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2001-08-22 | — | — | EP | disclosed |