Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 18/20 | 0.46 |
| ▸ | CA12 | O43570 | 17/20 | 0.46 |
| ▸ | CA1 | P00915 | 11/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.40 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.40 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6941415 | 0.91 | CA9 (0.47) | CA9CA12CA1KDM4EALDH1A1 | |
| SCHEMBL6935407 | 0.84 | CA9 (0.44) | CA9CA12CA1KDM4EALDH1A1 | |
| SCHEMBL6935413 | 0.82 | CA9 (0.43) | CA9CA12CA1KDM4EALDH1A1 | |
| SCHEMBL7649007 | 0.81 | KDM4E (0.43) | CA9CA12CA1KDM4EALDH1A1 | |
| SCHEMBL6937174 | 0.81 | KAT6A (0.46) | CA9CA12CA1ALDH1A1CA2 | |
| SCHEMBL6939342 | 0.79 | ALDH1A1 (0.39) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6938457 | 0.76 | BCAT1 (0.35) | — | |
| SCHEMBL7650712 | 0.75 | CA9 (0.45) | CA9CA12CA1KDM4EALDH1A1 | |
| SCHEMBL7650719 | 0.73 | CA9 (0.44) | CA9CA12CA1KDM4EALDH1A1 | |
| SCHEMBL7653443 | 0.73 | CA9 (0.42) | CA9CA12CA1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1125942-B1 | Derivatives of 6-amino or 6-hydrazinosulfonyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-09 | — | — | EP | claimed |
| EP-1125942-A1 | Derivatives of 6-amino or 6-hydrazinosulfonyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2001-08-22 | — | — | EP | claimed |
| EP-1125942-B1 | Derivatives of 6-amino or 6-hydrazinosulfonyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-09 | — | — | EP | disclosed |
| EP-1125942-A1 | Derivatives of 6-amino or 6-hydrazinosulfonyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2001-08-22 | — | — | EP | disclosed |