Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 17/20 | 0.42 |
| ▸ | CA2 | P00918 | 16/20 | 0.42 |
| ▸ | CA12 | O43570 | 12/20 | 0.42 |
| ▸ | CA9 | Q16790 | 12/20 | 0.42 |
| ▸ | CA7 | P43166 | 8/20 | 0.42 |
| ▸ | CA4 | P22748 | 7/20 | 0.42 |
| ▸ | CA6 | P23280 | 7/20 | 0.42 |
| ▸ | CA5A | P35218 | 7/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 7/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 7/20 | 0.42 |
| ▸ | CA3 | P07451 | 6/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 6/20 | 0.41 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | APEX1 | P27695 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6939756 | 0.86 | GRIN2D (0.33) | LMNAHSD17B10PMP22SMN1; SMN2TSHR | |
| SCHEMBL6934972 | 0.81 | CA2 (0.37) | CA1CA2CA12CA9CA7 | |
| SCHEMBL6940841 | 0.81 | KMT2A (0.35) | CA1CA2CA12CA9CA7 | |
| SCHEMBL6941830 | 0.81 | KDM4E (0.30) | CA1CA2LMNAHSD17B10PMP22 | |
| SCHEMBL6939365 | 0.81 | ALDH1A1 (0.49) | LMNASMN1; SMN2TSHR | |
| SCHEMBL6935418 | 0.78 | CA2 (0.46) | CA1CA2CA12CA9CA7 | |
| SCHEMBL6934900 | 0.77 | LMNA (0.33) | LMNATHRBPOLB | |
| SCHEMBL6937780 | 0.77 | ALDH1A1 (0.41) | SMN1; SMN2TSHRPOLB | |
| SCHEMBL6935282 | 0.77 | GSTO1 (0.38) | LMNA | |
| SCHEMBL6937936 | 0.76 | TSHR (0.49) | LMNASMN1; SMN2TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1125942-B1 | Derivatives of 6-amino or 6-hydrazinosulfonyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-09 | — | — | EP | disclosed |
| EP-1125941-B1 | Derivatives of 6-sulfamoyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-09 | — | — | EP | disclosed |
| EP-1125942-A1 | Derivatives of 6-amino or 6-hydrazinosulfonyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2001-08-22 | — | — | EP | disclosed |
| EP-1125941-A1 | Derivatives of 6-sulfamoyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2001-08-22 | — | — | EP | disclosed |