Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GPR88 | Q9GZN0 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4773039 | 0.76 | KIF11 (0.49) | HTR2AHTR2CHTR2BPOLBKIF11 | |
| SCHEMBL25456800 | 0.76 | KIF11 (0.49) | HTR2AHTR2CHTR2BPOLBKIF11 | |
| SCHEMBL28678691 | 0.76 | FFAR1 (0.50) | HTR2AHTR2CHTR2BCHRNB4CHRNA3 | |
| SCHEMBL25169879 | 0.76 | FFAR1 (0.50) | HTR2AHTR2CHTR2BCHRNB4CHRNA3 | |
| SCHEMBL4775489 | 0.76 | FFAR1 (0.50) | HTR2AHTR2CHTR2BCHRNB4CHRNA3 | |
| SCHEMBL28669621 | 0.76 | FFAR1 (0.50) | HTR2AHTR2CHTR2BCHRNB4CHRNA3 | |
| SCHEMBL6937906 | 0.74 | HTR2A (0.37) | HTR2AHTR2CHTR2BKDM1ACHRNB4 | |
| SCHEMBL6940894 | 0.73 | OPRM1 (0.48) | HTR2AHTR2CHTR2BDRD2OPRM1 | |
| SCHEMBL6934584 | 0.72 | CHRNB4 (0.48) | HTR2AHTR2CHTR2BKDM1ACHRNB4 | |
| SCHEMBL23923588 | 0.71 | HTR2A (0.56) | HTR2AHTR2CHTR2BKDM1ACHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1050528-B1 | Fungicidal and insecticidal benzyloxy cyclopropyl substituted aromatic compounds | DOW AGROSCIENCES LLC (US) | 2003-01-22 | — | — | EP | disclosed |
| US-6335367-B1 | Fungicidal and insecticidal benzyloxy cyclopropyl substituted aromatic compounds | DOW AGROSCIENCES LLC | 2002-01-01 | — | — | US | disclosed |
| EP-1050528-A1 | Fungicidal and insecticidal benzyloxy cyclopropyl substituted aromatic compounds | ROHM AND HAAS COMPANY (US) | 2000-11-08 | — | — | EP | disclosed |