Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6564706 | 0.90 | PTGS2 (0.54) | KMT2AL3MBTL1PTGS2CTSDALDH1A1 | |
| SCHEMBL6564711 | 0.88 | PTGS2 (0.55) | KMT2AL3MBTL1PTGS2ALDH1A1HSD17B10 | |
| SCHEMBL6942406 | 0.86 | HPGD (0.57) | KMT2AL3MBTL1CTSDALDH1A1HSD17B10 | |
| SCHEMBL6780943 | 0.83 | PTGS2 (0.53) | KMT2AL3MBTL1PTGS2ALDH1A1HSD17B10 | |
| SCHEMBL6779779 | 0.81 | CYP1A2 (0.62) | KMT2AL3MBTL1PTGS2ALDH1A1HSD17B10 | |
| SCHEMBL26942233 | 0.81 | PTGS2 (0.58) | KMT2AL3MBTL1PTGS2ALDH1A1HSD17B10 | |
| SCHEMBL6934863 | 0.80 | LMNA (0.46) | KMT2AL3MBTL1CTSDALDH1A1HSD17B10 | |
| SCHEMBL8626312 | 0.80 | KMT2A (0.69) | KMT2AL3MBTL1ALDH1A1HSD17B10ALOX15 | |
| SCHEMBL10144072 | 0.80 | HSD17B10 (0.67) | KMT2AL3MBTL1PTGS2ALDH1A1HSD17B10 | |
| SCHEMBL6939026 | 0.79 | KMT2A (0.63) | KMT2AL3MBTL1ALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272456-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | Abbott Laboratories (US) | 2003-01-08 | — | — | EP | claimed |
| WO-2001079157-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-10-25 | — | — | WO | claimed |