Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15178323 | 0.84 | HSPA5 (0.45) | HSPA5TSHRCYP2D6HIF1AHTR1A | |
| SCHEMBL23153080 | 0.83 | TSHR (0.50) | HSPA5TSHRCYP2D6HIF1AHTR1A | |
| SCHEMBL3959615 | 0.83 | TSHR (0.50) | HSPA5TSHRCYP2D6HIF1AHTR1A | |
| SCHEMBL1548303 | 0.82 | TRPA1 (0.42) | HSPA5TSHRMAPK1CA12CA2 | |
| SCHEMBL565137 | 0.81 | HSPA5 (0.50) | HSPA5TSHRCYP2D6HIF1ATAAR1 | |
| SCHEMBL9308109 | 0.80 | HTR1A (0.49) | HSPA5TSHRCYP2D6HIF1AHTR1A | |
| SCHEMBL14271048 | 0.80 | HTR1A (0.49) | HSPA5TSHRCYP2D6HIF1AHTR1A | |
| SCHEMBL8349103 | 0.79 | TAAR1 (0.42) | CYP2D6TAAR1CYP3A4SLC6A2SLC6A4 | |
| SCHEMBL4232504 | 0.79 | HSPA5 (0.48) | HSPA5TSHRCYP2D6HIF1AHTR1A | |
| SCHEMBL6424581 | 0.79 | TAAR1 (0.42) | CYP2D6TAAR1CYP3A4SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101909592-B | External preparation for skin | KAO CORP | 2013-01-30 | — | — | CN | disclosed |
| CN-101909586-B | Skin external preparation for acne skin | KAO CORP | 2013-01-02 | — | — | CN | disclosed |
| CN-101909586-A | Skin external preparation for acne skin | KAO CORP | 2010-12-08 | — | — | CN | disclosed |
| CN-101909592-A | External preparation for skin | KAO CORP | 2010-12-08 | — | — | CN | disclosed |
| US-20040076690-A1 | Compositions for weight loss with improved taste | KANEBO, LTD. (JP) | 2004-04-22 | — | — | US | disclosed |
| JP-2003342223-A | CLATHRATE COMPOUND AND COMPOSITION CONTAINING THE SAME | KANEBO LTD | 2003-12-03 | — | — | JP | disclosed |
| US-4129413-A | Oxidation hair dyes based upon tetraaminopyrimidine developers and mono- and dialkyl -m- dihydroxy benzene couplers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 1978-12-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040076690-A1 | Compositions for weight loss with improved taste | FABP4, FABP6, TAS2R60 | HSPA5 1999/4885TSHR 2549/4885CYP2D6 4530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.