Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.40 |
| ▸ | PPARA | Q07869 | 14/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | IAPP | P10997 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936615 | 0.85 | PPARG (0.36) | PPARGPPARALMNAMAPTXBP1 | |
| SCHEMBL6940834 | 0.70 | FABP3 (0.44) | PPARGPPARA | |
| SCHEMBL5704723 | 0.69 | PPARG (0.33) | PPARGPPARA | |
| SCHEMBL11074276 | 0.67 | CYP4F2 (0.38) | PPARGPPARALTB4RLTB4R2DAO | |
| SCHEMBL28455439 | 0.66 | SMN1; SMN2 (0.47) | PPARGPPARALMNAMAPTHIF1A | |
| SCHEMBL185493 | 0.65 | KCNH2 (0.33) | — | |
| SCHEMBL1452942 | 0.65 | ALDH1A1 (0.41) | LTB4RLTB4R2DAOIAPP | |
| Hydrogen Peroxide SCHEMBL28975560 | 0.64 | GABRA1 (0.48) | PPARGPPARALTB4RLTB4R2DAO | |
| SCHEMBL1005994 | 0.64 | GABRA1 (0.38) | LTB4RLTB4R2DAOIAPP | |
| SCHEMBL20954028 | 0.64 | KMT2A (0.46) | PPARGPPARALTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003513909-A | — | — | 2003-04-15 | — | — | JP | claimed |
| EP-1229907-A1 | PREVENTION OF PLAQUE RUPTURE BY ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2002-08-14 | — | — | EP | claimed |
| WO-2001034127-A1 | PREVENTION OF PLAQUE RUPTURE BY ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-05-17 | — | — | WO | claimed |
| EP-1229907-A1 | PREVENTION OF PLAQUE RUPTURE BY ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001034127-A1 | PREVENTION OF PLAQUE RUPTURE BY ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-05-17 | — | — | WO | disclosed |