Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 10/20 | 0.37 |
| ▸ | PPARA | Q07869 | 10/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7206360 | 0.83 | FABP3 (0.51) | FABP3FABP4SOAT2MYCSOAT1 | |
| SCHEMBL7207662 | 0.79 | FABP4 (0.58) | FABP3FABP4SOAT2MYCSOAT1 | |
| SCHEMBL27898710 | 0.72 | FABP3 (0.62) | FABP3FABP4SOAT2MYCSOAT1 | |
| SCHEMBL6940243 | 0.71 | FABP3 (0.39) | FABP3FABP4SOAT2MYCSOAT1 | |
| SCHEMBL6940643 | 0.70 | PPARG (0.40) | PPARGPPARA | |
| SCHEMBL19289770 | 0.69 | GABRA1 (0.50) | SOAT1HSP90AB1GABRA1GABRG2GABRB3 | |
| SCHEMBL2380508 | 0.68 | FABP4 (0.60) | FABP3FABP4SOAT2MYCSOAT1 | |
| SCHEMBL19289798 | 0.67 | GABRA1 (0.44) | HSP90AB1GABRA1GABRG2GABRB3GABRB2 | |
| SCHEMBL4327412 | 0.66 | FABP3 (0.58) | FABP3FABP4SOAT2MYCSOAT1 | |
| SCHEMBL20274264 | 0.65 | FABP3 (0.72) | FABP3FABP4PPARGFABP5HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003513909-A | — | — | 2003-04-15 | — | — | JP | claimed |
| EP-1229907-A1 | PREVENTION OF PLAQUE RUPTURE BY ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2002-08-14 | — | — | EP | claimed |
| WO-2001034127-A1 | PREVENTION OF PLAQUE RUPTURE BY ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-05-17 | — | — | WO | claimed |