Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MGAM | O43451 | 1/20 | 0.55 |
| ▸ | SI | P14410 | 1/20 | 0.55 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.55 |
| ▸ | MET | P08581 | 1/20 | 0.53 |
| ▸ | SMO | Q99835 | 1/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.51 |
| ▸ | CES1 | P23141 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9386982 | 0.91 | MEN1 (0.54) | MAPTMEN1KMT2ALMNARAB9A | |
| SCHEMBL9334168 | 0.89 | GPR84 (0.59) | MAPTMEN1KMT2ALMNARAB9A | |
| SCHEMBL8792576 | 0.85 | F7 (0.53) | MAPTMEN1KMT2ALMNAXDH | |
| SCHEMBL8793654 | 0.85 | MET (0.66) | MAPTMEN1KMT2ALMNARAB9A | |
| SCHEMBL15712665 | 0.83 | GABRP (0.61) | — | |
| SCHEMBL31380217 | 0.82 | GABRP (0.56) | MAPTMEN1KMT2ALMNARAB9A | |
| SCHEMBL31324677 | 0.80 | PKM (0.45) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL298527 | 0.80 | MET (0.56) | MAPTMEN1KMT2ALMNARAB9A | |
| SCHEMBL29567770 | 0.80 | GPR84 (0.57) | MAPTMEN1KMT2ALMNARAB9A | |
| SCHEMBL22634965 | 0.79 | GPR84 (0.65) | RAB9AGPR84TP53ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6515141-B1 | Process for the preparation of indole derivatives or salts thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-02-04 | — | — | US | disclosed |
| CN-1382123-A | Process for preparation of indole derivatives or salts thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-11-27 | — | — | CN | disclosed |
| EP-1207153-A1 | PROCESS FOR THE PREPARATION OF INDOLE DERIVATIVES OR SALTS THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-22 | — | — | EP | disclosed |
| EP-0458207-B1 | Indole derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-03-26 | — | — | EP | disclosed |
| CN-1030701-C | Indole derivatives and process for production thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-01-17 | — | — | CN | disclosed |
| EP-0603278-A1 | INDOLE DERIVATIVES AS 5-ALPHA-REDUCTASE INHIBITOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-29 | — | — | EP | disclosed |
| US-5312829-A | Testosterone 5alpha-reductase inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| US-5212320-A | Enzyme inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-05-18 | — | — | US | disclosed |
| WO-1993005019-A1 | INDOLE DERIVATIVES AS 5-ALPHA-REDUCTASE INHIBITOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-18 | — | — | WO | disclosed |
| CN-1056685-A | Indole derivatives and preparation method thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1991-12-04 | — | — | CN | disclosed |
| EP-0458207-A2 | Indole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |