Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 3/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6404796 | 1.00 | HTT (0.59) | HTTFOLH1LMNASMN1; SMN2CTSK | |
| SCHEMBL6943807 | 0.89 | HTT (0.50) | HTTLMNASMN1; SMN2CTSKCTSS | |
| SCHEMBL6946489 | 0.89 | HTT (0.50) | HTTLMNASMN1; SMN2CTSKCTSS | |
| SCHEMBL2723527 | 0.87 | LMNA (0.52) | HTTLMNASMN1; SMN2CTSKCTSS | |
| SCHEMBL18086889 | 0.87 | CTSK (0.55) | HTTLMNASMN1; SMN2CTSKCTSS | |
| SCHEMBL6940875 | 0.87 | HSD17B10 (0.50) | HTTLMNASMN1; SMN2CTSKCTSS | |
| SCHEMBL6943800 | 0.87 | HSD17B10 (0.50) | HTTLMNASMN1; SMN2CTSKCTSS | |
| SCHEMBL7533308 | 0.86 | LMNA (0.51) | HTTLMNASMN1; SMN2CTSKCTSS | |
| SCHEMBL7535276 | 0.86 | LMNA (0.51) | HTTLMNASMN1; SMN2CTSKCTSS | |
| SCHEMBL2722875 | 0.86 | LMNA (0.51) | HTTLMNASMN1; SMN2CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |