Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.48 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.48 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6943800 | 1.00 | HSD17B10 (0.50) | HSD17B10HTTBCHEACHECACNA1F | |
| SCHEMBL28017164 | 0.88 | HTT (0.48) | HSD17B10HTTBCHEACHECACNA1F | |
| SCHEMBL6404796 | 0.87 | HTT (0.59) | HTTSYKLMNASMN1; SMN2CTSK | |
| SCHEMBL6940690 | 0.87 | HTT (0.59) | HTTSYKLMNASMN1; SMN2CTSK | |
| SCHEMBL18086889 | 0.85 | CTSK (0.55) | HSD17B10HTTSYKLMNASMN1; SMN2 | |
| SCHEMBL28869105 | 0.85 | HSD17B10 (0.46) | HSD17B10HTTBCHEACHECACNA1F | |
| SCHEMBL6943807 | 0.85 | HTT (0.50) | HTTSYKLMNASMN1; SMN2CTSK | |
| SCHEMBL6946489 | 0.85 | HTT (0.50) | HTTSYKLMNASMN1; SMN2CTSK | |
| SCHEMBL18085401 | 0.83 | CTSL (0.57) | HSD17B10HTTSYKLMNASMN1; SMN2 | |
| SCHEMBL2723527 | 0.83 | LMNA (0.52) | HTTSYKLMNASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |